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How to get fromMiddlesboro to Greenvilleby car, plane, or bus

Find Transport to Greenville

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There are 3 ways to get from Middlesboro to Greenville by car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, fly

    best
    1. Drive from Middlesboro to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Greenville–Spartanburg International Airport (GSP)plane plane TYS - GSP
    5h
    $143–714

  2. Drive 188.2 mi

    cheapest
    1. Drive from Middlesboro to Greenvillecar car 188.2 mi
    3h 53m
    $35–50

  3. Drive, bus

    1. Drive from Middlesboro to Londoncar car
    2. Take the bus from London to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    12h 34m
    $120–279

Mcghee Tyson Airport (TYS) to Greenville–Spartanburg International Airport (GSP) flights

Calendar104Weekly Planes
Duration4h 16mAverage Duration
Ticket$96Cheapest Price
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Questions & Answers

Map of how to get from Middlesboro to Greenville.ExpandLaunch map view
  • Distance: 203.2 mi
  • Duration: 5h

What companies run services between Middlesboro, KY, USA and Greenville, SC, USA?

There is no direct connection from Middlesboro to Greenville. However, you can drive to Mcghee Tyson Airport (TYS) airport, fly to Greenville–Spartanburg International Airport (GSP), then take the taxi to Greenville. Alternatively, you can take a vehicle from Middlesboro to Greenville via London, Atlanta Bus Station, Garnett Station, Lindbergh Center Station, Lindbergh Center Station - Bay D, Shallowford Rd @ New Peachtree, Atlanta, and Taqueria Guadalajara - Greenville in around 12h 34m.

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