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How to get fromMiddleton to Louisvilleby plane, bus (Amtrak), bus, train, car, or bus (Flixbus)

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There are 10 ways to get from Middleton to Louisville by plane, bus (Amtrak), bus, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Dane County Regional Airport-Truax Field to Louisville International Airport

    best
    1. Fly from Dane County Regional Airport-Truax Field (MSN) to Louisville International Airport (SDF)plane plane MSN - SDF
    7h 15m
    $115–657

  2. Bus via Chicago

    cheapest
    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus Van Galder
    2. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    13h 13m
    $78–122

  3. Bus, train via Milwaukee

    1. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    14h 48m
    $123–260

  4. Drive 445.7 mi

    1. Drive from Middleton to Louisvillecar car 445.7 mi
    7h 45m
    $82–118

  5. Bus to Chicago O'Hare International Airport, fly to Louisville International Airport

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    7h 51m
    $91–475

  6. Bus to General Mitchell International Airport, fly to Louisville International Airport

    1. Take the bus from Madison, WI-Lake St. to Milwaukee, WI - Amtrakbus bus
    2. Fly from General Mitchell International Airport (MKE) to Louisville International Airport (SDF)plane plane MKE - SDF
    8h 41m
    $117–692

  7. Bus to Chicago O'Hare International Airport, fly to Blue Grass Airport, drive

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    8h
    $138–721

  8. Bus to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    8h 57m
    $110–615

  9. Bus

    1. Take the bus from Madison to Cincinnatibus bus FlixBus 2514
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus Cleveland
    14h 28m
    $82–180

  10. Bus, train

    1. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    14h 38m
    $110–237

Middleton to Louisville by bus

Calendar14Weekly Buses
Duration13h 13mAverage Duration
Ticket$78Cheapest Price
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Questions & Answers

Map of how to get from Middleton to Louisville.ExpandLaunch map view
  • Distance: 411.2 mi
  • Duration: 7h 15m

What companies run services between Middleton, WI, USA and Louisville, KY, USA?

United Airlines, American Airlines, and Delta fly from Dane County Regional Airport-Truax Field (MSN) to Louisville International Airport (SDF) hourly. Alternatively, you can take a bus from Park at Elmwood to Louisville, KY via W Johnson at East Campus, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Union Station in around 13h 13m.

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