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How to get fromMiddletown to Buffaloby bus (Greyhound), train (Amtrak), car, bus, train, or plane

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There are 9 ways to get from Middletown to Buffalo by bus (Greyhound), train (Amtrak), car, bus, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Hartford Union Station to Springfield Union Stationbus bus Greyhound US0240 / ...
    2. Take the bus from Springfield Union Station to Buffalobus bus Greyhound US0171
    11h 35m
    $61–132

  2. Train

    1. Take the train from Hartford Amtrak Station to Springfieldtrain train
    2. Take the train from Springfield to Albany-Rensselaer Amtrak Stationtrain train
    3. Take the train from Albany-Rensselaer Amtrak Station to Buffalotrain train
    12h 32m
    $120–331

  3. Drive 398.7 mi

    1. Drive from Middletown to Buffalocar car 398.7 mi
    7h 31m
    $73–106

  4. Bus, train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Downtown Terminal to Stage Rd & Route 1bus bus
    2. Take the train from Old Saybrook Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    8h 1m
    $123–575

  5. Bus via New York

    1. Take the bus from Hartford Union Station to Port Authority Bus Terminalbus bus Boston
    2. Take the bus from New York to Buffalobus bus Adt N816 / ...
    13h 26m
    $86–349

  6. Bus, train, train to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Downtown Terminal to Stage Rd & Route 1bus bus
    2. Take the train from Old Saybrook Amtrak Station to Stamford Amtrak Stationtrain train
    3. Take the train from Stamford to 125th Street - Harlemtrain train
    4. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    8h 18m
    $130–706

  7. Bus, train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Downtown Terminal to Stage Rd & Route 1bus bus
    2. Take the train from Old Saybrook Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    8h 13m
    $129–594

  8. Line 55 bus, line 926 bus, bus to Boston Logan Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Main St @ Ferry St to Main St @ 750 Main Stbus bus
    2. Take the bus from Central Row @ Main St to Canton Park & Ridebus bus
    3. Take the bus from Canton Park & Ride to Boston Airportbus bus
    4. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    7h 48m
    $107–559

  9. Bus, train, train to Laguardia Airport, fly to Rochester

    1. Take the bus from Downtown Terminal to Stage Rd & Route 1bus bus
    2. Take the train from Old Saybrook Amtrak Station to Stamford Amtrak Stationtrain train
    3. Take the train from Stamford to 125th Street - Harlemtrain train
    4. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    5. Take the bus from Rochester Bus Stop to Buffalobus bus
    9h 56m
    $162–771

Middletown to Buffalo by bus and foot (Greyhound)

Calendar7Weekly Services
Duration11h 35mAverage Duration
Ticket$61Cheapest Price
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Questions & Answers

Map of how to get from Middletown to Buffalo.ExpandLaunch map view
  • Distance: 430.4 mi
  • Duration: 11h 35m

What companies run services between Middletown, CT, USA and Buffalo, NY, USA?

You can take a bus from Main St @ Ferry St to Buffalo via Main St @ 750 Main St, Hartford Union Station, and Springfield Union Station in around 11h 35m. Alternatively, you can take a bus from Silver St @ Silver St Park & Ride to Buffalo via Asylum St @ Union Pl, Hartford Amtrak Station, Springfield, and Albany-Rensselaer Amtrak Station in around 12h 32m.

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