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How to get fromMiddletown Ny to Buffalo Depew Stationby train, plane, bus, car, or bus (Flixbus, Greyhound)

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There are 8 ways to get from Middletown Ny to Buffalo Depew Station by train, plane, bus, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Middletown Ny to Secaucus Lower Leveltrain train
    2. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    4h 37m
    $103–525

  2. Drive 302.1 mi

    cheapest
    1. Drive from Middletown Ny to Buffalo Depew Stationcar car 302.1 mi
    6h 3m
    $56–80

  3. Bus, train

    1. Take the bus from Middletown to Syracusebus bus Adt A144
    2. Take the train from Syracuse Regional Transportation Center to Buffalo Depew Stationtrain train Empire Service / ...
    7h 43m
    $67–303

  4. Train

    1. Take the train from Middletown Ny to Secaucus Lower Leveltrain train Mnbnp
    2. Take the train from New York Penn Station to Buffalotrain train VIA Rail
    11h 1m
    $115–325

  5. Train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Middletown Ny to Secaucus Lower Leveltrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    4h 53m
    $100–518

  6. Train to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Middletown Ny to Secaucus Lower Leveltrain train
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    5h 32m
    $114–666

  7. Train to Newark Liberty International Airport, fly to Rochester, train

    1. Take the train from Middletown Ny to Secaucus Lower Leveltrain train
    2. Fly from Newark Liberty International Airport (EWR) to Rochester (ROC)plane plane EWR - ROC
    3. Take the train from Rochester to Buffalo Depew Stationtrain train
    6h 40m
    $526–1,833

  8. Bus

    1. Take the bus from Middletown to Syracusebus bus Adt A144
    2. Take the bus from Syracuse Bus Station to Buffalobus bus FlixBus 2686 / ...
    10h 6m
    $64–212

Middletown Ny to Buffalo Depew Station by train

Calendar7Weekly Trains
Duration11h 1mAverage Duration
Ticket$115Cheapest Price
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Questions & Answers

Map of how to get from Middletown Ny to Buffalo Depew Station.ExpandLaunch map view
  • Distance: 359.8 mi
  • Duration: 4h 37m

What companies run services between Middletown Ny, NY, USA and Buffalo Depew Station, NY, USA?

You can take a train from Middletown Ny to Buffalo via Secaucus Upper Level and New York Penn Station in around 11h 1m. Alternatively, you can take a vehicle from Middletown Ny to Buffalo Depew Station via Middletown, Syracuse Bus Station, Ellicott Street & MTC Static, Walden Avenue & Thruway Transit Center, and Walden Avenue & 2929 Walden Avenue in around 10h 6m.

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