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How to get fromMiddletown Ny to Florenceby bus, train (Amtrak), car, train, or plane

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There are 12 ways to get from Middletown Ny to Florence by bus, train (Amtrak), car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Middletown to New Yorkbus bus Adt A141 / ...
    2. Take the bus from New York, NY to Florence, SCbus bus Nyc
    15h 35m
    $111–192

  2. Train

    1. Take the train from Middletown Ny to Secaucus Lower Leveltrain train Mnbnp
    2. Take the train from Newark Penn Station to Florence Stationtrain train Palmetto / ...
    17h 13m
    $195–445

  3. Drive 654.1 mi

    1. Drive from Middletown Ny to Florencecar car 654.1 mi
    12h 39m
    $120–173

  4. Train to Newark Liberty International Airport, fly to Myrtle Beach, bus, train

    1. Take the train from Middletown Ny to Secaucus Lower Leveltrain train
    2. Fly from Newark Liberty International Airport (EWR) to Myrtle Beach (MYR)plane plane EWR - MYR
    3. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    4. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    11h 5m
    $427–909

  5. Train, bus

    1. Take the train from Middletown Ny to Hobokentrain train
    2. Take the bus from Hoboken Terminal to Port Authority Bus Terminalbus bus 126
    3. Take the bus from Port Authority Bus Terminal to Raleigh Bus Stationbus bus
    4. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    16h 45m
    $112–253

  6. Train to Newark Liberty International Airport, fly to Raleigh-Durham International Airport, bus, train

    1. Take the train from Middletown Ny to Secaucus Lower Leveltrain train
    2. Fly from Newark Liberty International Airport (EWR) to Raleigh-Durham International Airport (RDU)plane plane EWR - RDU
    3. Take the bus from Raleigh Bus Station to Fayetteville Bus Stationbus bus
    4. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train
    11h 37m
    $252–1,130

  7. Train to Laguardia Airport, fly to Columbia, bus

    1. Take the train from Middletown Ny to Secaucus Lower Leveltrain train
    2. Fly from Laguardia Airport (LGA) to Columbia (CAE)plane plane LGA - CAE
    3. Take the bus from Columbia, SC to Camdenbus bus
    4. Take the bus from Camden to Florence Bus Stationbus bus
    12h 4m
    $272–1,310

  8. Train to Laguardia Airport, fly to Myrtle Beach, bus, train

    1. Take the train from Middletown Ny to Secaucus Lower Leveltrain train
    2. Fly from Laguardia Airport (LGA) to Myrtle Beach (MYR)plane plane LGA - MYR
    3. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    4. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    11h 54m
    $138–560

  9. Train to Laguardia Airport, fly to Raleigh-Durham International Airport, bus, train

    1. Take the train from Middletown Ny to Secaucus Lower Leveltrain train
    2. Fly from Laguardia Airport (LGA) to Raleigh-Durham International Airport (RDU)plane plane LGA - RDU
    3. Take the bus from Raleigh Bus Station to Fayetteville Bus Stationbus bus
    4. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train
    12h 35m
    $223–571

  10. Fly Stewart International Airport to Myrtle Beach, bus, train

    1. Fly from Stewart International Airport (SWF) to Myrtle Beach (MYR)plane plane SWF - MYR
    2. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    3. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    11h 10m
    $401–875

  11. Train, bus to Lehigh Valley International Airport, fly to Myrtle Beach, bus

    1. Take the train from Middletown Ny to Secaucus Lower Leveltrain train
    2. Take the bus from Newark Airport Terminal B to Lehigh Valley International Airport Trans Bridge Bus Stopbus bus
    3. Fly from Lehigh Valley International Airport (ABE) to Myrtle Beach (MYR)plane plane ABE - MYR
    4. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    5. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    13h 56m
    $182–529

  12. Train to Westchester County Airport, fly to Myrtle Beach, bus, train

    1. Take the train from Middletown Ny to Sufferntrain train
    2. Fly from Westchester County Airport (HPN) to Myrtle Beach (MYR)plane plane HPN - MYR
    3. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    4. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    13h 32m
    $244–1,237

Middletown Ny to Florence by train

Calendar14Weekly Trains
Duration17h 13mAverage Duration
Ticket$195Cheapest Price
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Questions & Answers

Map of how to get from Middletown Ny to Florence.ExpandLaunch map view
  • Distance: 771.9 mi
  • Duration: 15h 35m

What companies run services between Middletown Ny, NY, USA and Florence, SC, USA?

You can take a vehicle from Middletown Ny to Florence, SC via Middletown, New York, 42 St-Port Authority Bus Terminal, Chambers St, Warren St/Church St, East Broadway/Pike St, and New York, NY in around 15h 35m. Alternatively, you can take a train from Middletown Ny to Florence Station via Secaucus Upper Level and Newark Penn Station in around 17h 13m.

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