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How to get fromMiddletown to St. Louisby bus, plane, bus (Greyhound), taxi, train, or car

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There are 8 ways to get from Middletown to St. Louis by bus, plane, bus (Greyhound), taxi, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Laguardia Airport, fly

    best
    1. Take the bus from Railroad Ave - Middletown Terminal to Port Authority Bus Terminalbus bus
    2. Fly from Laguardia Airport (LGA) to Lambert–St. Louis International Airport (STL)plane plane LGA - STL
    6h 37m
    $160–475

  2. Bus to John F. Kennedy International Airport, fly

    cheapest
    1. Take the bus from Railroad Ave - Middletown Terminal to Port Authority Bus Terminalbus bus
    2. Fly from John F. Kennedy International Airport (JFK) to Lambert–St. Louis International Airport (STL)plane plane JFK - STL
    7h 14m
    $151–651

  3. Bus

    1. Take the bus from Railroad Ave - Middletown Terminal to Port Authority Bus Terminalbus bus ShortLine Hudson
    2. Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus bus Greyhound US0421
    25h 45m
    $164–329

  4. Taxi, train (Amtrak)

    1. Take the taxi from Middletown to Beacontaxi taxi
    2. Take the train from Poughkeepsie Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    25h 46m
    $512–981

  5. Drive 956.5 mi

    1. Drive from Middletown to St. Louiscar car 956.5 mi
    16h 5m
    $175–253

  6. Bus, bus to Newark Liberty International Airport, fly

    1. Take the bus from Railroad Ave - Middletown Terminal to Port Authority Bus Terminalbus bus
    2. Take the bus from Port Authority Bus Terminal to Terminal Bbus bus
    3. Fly from Newark Liberty International Airport (EWR) to Lambert–St. Louis International Airport (STL)plane plane EWR - STL
    6h 59m
    $392–957

  7. Bus to Westchester County Airport, fly

    1. Take the bus from Railroad Ave - Middletown Terminal to Main St & Broadwaybus bus
    2. Fly from Westchester County Airport (HPN) to Lambert–St. Louis International Airport (STL)plane plane HPN - STL
    9h 29m
    $218–1,030

  8. Bus, train to Philadelphia International Airport, fly

    1. Take the bus from Railroad Ave - Middletown Terminal to Port Authority Bus Terminalbus bus
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Lambert–St. Louis International Airport (STL)plane plane PHL - STL
    8h 8m
    $190–1,385

Middletown to St. Louis by bus

Calendar21Weekly Buses
Duration25h 45mAverage Duration
Ticket$164Cheapest Price
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Questions & Answers

Map of how to get from Middletown to St. Louis.ExpandLaunch map view
  • Distance: 984.5 mi
  • Duration: 6h 37m

What companies run services between Middletown, Orange County, NY, USA and St. Louis, MO, USA?

You can take a bus from Railroad Ave - Middletown Terminal to St Louis Bus Station via Port Authority Bus Terminal in around 25h 45m.

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