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How to get fromMiddletown to Knoxvilleby train, plane, bus, or car

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There are 7 ways to get from Middletown to Knoxville by train, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Newark Liberty International Airport, fly to Mcghee Tyson Airport

    best
    1. Take the train from Middletown Nj to Newark Airport Railroad Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Mcghee Tyson Airport (TYS)plane plane EWR - TYS
    4h 23m
    $230–1,001

  2. Train to Newark Liberty International Airport, fly to Asheville Regional Airport, drive

    cheapest
    1. Take the train from Middletown Nj to Newark Airport Railroad Stationtrain train
    2. Fly from Newark Liberty International Airport (EWR) to Asheville Regional Airport (AVL)plane plane EWR - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    6h 13m
    $117–466

  3. Train, bus via Farragut

    1. Take the train from Middletown Nj to New York Penn Stationtrain train Njcl / ...
    2. Take the bus from New York to Knoxvillebus bus Nyc
    14h 56m
    $186–271

  4. Drive  677.9 mi

    1. Drive from Middletown to Knoxvillecar car 677.9 mi
    12h 8m
    $124–179

  5. Train to Laguardia Airport, fly to Mcghee Tyson Airport

    1. Take the train from Middletown Nj to New York Penn Stationtrain train
    2. Fly from Laguardia Airport (LGA) to Mcghee Tyson Airport (TYS)plane plane LGA - TYS
    5h 46m
    $251–1,191

  6. Train, train to Philadelphia International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Middletown Nj to Newark Penn Stationtrain train
    2. Take the train from Newark Penn Station to 30th Street Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Mcghee Tyson Airport (TYS)plane plane PHL - TYS
    6h 21m
    $248–1,690

  7. Train, bus

    1. Take the train from Middletown Nj to New York Penn Stationtrain train Njcl / ...
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    15h
    $141–181

Newark Liberty International Airport (EWR) to Mcghee Tyson Airport (TYS) flights

Calendar58Weekly Planes
Duration3h 57mAverage Duration
Ticket$159Cheapest Price
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Comparing Your Travel Options

Map of how to get from Middletown to Knoxville.ExpandLaunch map view
  • Distance: 672.9 mi
  • Duration: 4h 23m

What companies run services between Middletown, Monmouth County, NJ, USA and Knoxville, TN, USA?

There is no direct connection from Middletown to Knoxville. However, you can take the train to Newark Airport Railroad Station, walk to Newark Airport Railroad Station, take the vehicle to Terminal B, walk to Newark Liberty International Airport (EWR) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take a train from Middletown Nj to Knoxville via Penn Station, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 14h 56m.

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