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How to get fromMidtown Detroit to Chicagoby train (Amtrak), bus (Amtrak), car, plane, bus (Greyhound, Flixbus), train, or bus

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There are 8 ways to get from Midtown Detroit to Chicago by train (Amtrak), bus (Amtrak), car, plane, bus (Greyhound, Flixbus), train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Detroit to Chicago Union Stationtrain train Wolverine
    6h 14m
    $75–170

  2. Bus via Lafayette & Fifth

    cheapest
    1. Take the bus from Detroit Bus Station to Chicago Bus Stationbus bus Greyhound US0160
    7h 25m
    $44–84

  3. Bus (Amtrak)

    1. Take the bus from Detroit to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    6h 35m
    $86–132

  4. Drive  279.9 mi

    1. Drive from Midtown Detroit to Chicagocar car 279.9 mi
    4h 39m
    $52–74

  5. Fly Detroit to Chicago Midway International Airport

    1. Fly from Detroit (DTW) to Chicago Midway International Airport (MDW)plane plane DTW - MDW
    4h 21m
    $136–469

  6. Fly Detroit to Chicago O'Hare International Airport

    1. Fly from Detroit (DTW) to Chicago O'Hare International Airport (ORD)plane plane DTW - ORD
    4h 37m
    $136–709

  7. Fly Detroit to South Bend, train

    1. Fly from Detroit (DTW) to South Bend (SBN)plane plane DTW - SBN
    2. Take the train from South Bend Airport to Van Buren St.train train
    6h 31m
    $92–619

  8. Bus to Bishop International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Detroit Bus Station to Flintbus bus
    2. Fly from Bishop International Airport (FNT) to Chicago O'Hare International Airport (ORD)plane plane FNT - ORD
    6h 9m
    $48–272

Midtown Detroit to Chicago by tram and train (Amtrak)

Calendar21Weekly Services
Duration6h 14mAverage Duration
Ticket$75Cheapest Price
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Questions & Answers

Map of how to get from Midtown Detroit to Chicago.ExpandLaunch map view
  • Distance: 281.6 mi
  • Duration: 6h 14m

What companies run services between Midtown Detroit, MI, USA and Chicago, IL, USA?

Amtrak operates a train from Detroit to Chicago Union Station 3 times a day. Tickets cost $75–170 and the journey takes 5h 6m. Alternatively, Amtrak operates a bus from Detroit to Chicago Union Station once a week. Tickets cost $85–130 and the journey takes 5h 27m.

Airlines
Train operators
Bus operators

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