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How to get fromMidtown Manhattan to Buffaloby subway, plane, bus, train, car, or bus (Flixbus)

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There are 8 ways to get from Midtown Manhattan to Buffalo by subway, plane, bus, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Subway to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the subway from 5 Av/53 St to Sutphin Blvd-Archer Av-JFK Airportsubway subway
    2. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    3h 54m
    $84–501

  2. Bus

    cheapest
    1. Take the bus from New York to Buffalobus bus Adt N816 / ...
    8h
    $60–280

  3. Train

    1. Take the train from New York Penn Station to Buffalotrain train VIA Rail
    9h 36m
    $113–293

  4. Drive 358.4 mi

    1. Drive from Midtown Manhattan to Buffalocar car 358.4 mi
    7h 15m
    $66–95

  5. Bus to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Port Authority Bus Terminal to Terminal Bbus bus
    2. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    4h
    $97–534

  6. Subway to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the subway from 5 Av/53 St to Jackson Hts-Roosevelt Avsubway subway
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    4h 31m
    $98–640

  7. Bus to Newark Liberty International Airport, fly to Rochester, bus

    1. Take the bus from Port Authority Bus Terminal to Terminal Bbus bus
    2. Fly from Newark Liberty International Airport (EWR) to Rochester (ROC)plane plane EWR - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 40m
    $523–1,668

  8. Bus via 5 Av/W 52 St (Flixbus)

    1. Take the bus from New York Midtown to Buffalobus bus FlixBus N2686 / ...
    9h 48m
    $63–117

Midtown Manhattan to Buffalo by bus

Calendar45Weekly Buses
Duration8hAverage Duration
Ticket$60Cheapest Price
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Questions & Answers

Map of how to get from Midtown Manhattan to Buffalo.ExpandLaunch map view
  • Distance: 330 mi
  • Duration: 3h 54m

What companies run services between Midtown Manhattan, NY, USA and Buffalo, NY, USA?

Trailways operates a bus from New York to Buffalo every 4 hours. Tickets cost $60–280 and the journey takes 8h. Alternatively, VIA Rail operates a train from New York Penn Station to Buffalo once daily. Tickets cost $110–290 and the journey takes 8h 24m.

Airlines
Train operators
Bus operators

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