Rome2Rio

How to get fromMidtown Manhattan to Buffaloby bus, plane, bus (Flixbus), train, car, or subway

Find Transport to Buffalo

See all options

There are 8 ways to get from Midtown Manhattan to Buffalo by bus, plane, bus (Flixbus), train, car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the bus from Port Authority Bus Terminal to Terminal Bbus bus
    2. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    3h 58m
    $92–527

  2. Bus

    cheapest
    1. Take the bus from New York to Buffalobus bus Adt N816 / ...
    8h
    $65–110

  3. Train

    1. Take the train from New York Penn Station to Buffalotrain train VIA Rail
    8h 24m
    $110–290

  4. Drive  358.6 mi

    1. Drive from Midtown Manhattan to Buffalocar car 358.6 mi
    7h 14m
    $66–95

  5. Subway to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    1. Take the subway from 5 Av/53 St to Sutphin Blvd-Archer Av-JFK Airportsubway subway
    2. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    3h 56m
    $79–454

  6. Line 6 subway, bus to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the subway from Lexington Avenue/59th Street to 125th Streetsubway subway
    2. Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus bus
    3. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    4h 3m
    $93–613

  7. Bus to Newark Liberty International Airport, fly to Rochester, bus

    1. Take the bus from Port Authority Bus Terminal to Terminal Bbus bus
    2. Fly from Newark Liberty International Airport (EWR) to Rochester (ROC)plane plane EWR - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 41m
    $534–1,710

  8. Fly Laguardia Airport to Rochester, bus

    1. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 45m
    $135–806

Midtown Manhattan to Buffalo by bus

Calendar76Weekly Buses
Duration8hAverage Duration
Ticket$65Cheapest Price
See schedules

Questions & Answers

Map of how to get from Midtown Manhattan to Buffalo.ExpandLaunch map view
  • Distance: 355.6 mi
  • Duration: 3h 58m

What companies run services between Midtown Manhattan, NY, USA and Buffalo, NY, USA?

Trailways operates a bus from New York to Buffalo every 4 hours. Tickets cost $60–280 and the journey takes 8h. Flixbus USA also services this route 5 times a day. Alternatively, VIA Rail operates a train from New York Penn Station to Buffalo once daily. Tickets cost $110–290 and the journey takes 8h 24m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers