There are 10 ways to get from Milan to Karlsruhe by train (Trenitalia), bus, night train, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Trenitalia)
best- Take the train from Milano Centrale to Karlsruhe Hbftrain Ec
6h 19m€110–170Bus, night train
cheapest- Take the bus from Milano, Autostazione Lampugnano to Zürichbus BlaBlaCar Bus
- Take the nighttrain from Zuerich Hb to Karlsruhe Hbfnighttrain Nj
8h 4m€42–125Drive 528.3 km
- Drive from Milan to Karlsruhecar 528.3 km
5h 12m€86–123Fly Milan Linate Airport to Stuttgart Airport, train
- Fly from Milan Linate Airport (LIN) to Stuttgart Airport (STR)plane LIN - STR
- Take the train from Stuttgart Hbf to Karlsruhe Hbftrain
4h 47m€128–366Train via Basel
- Take the train from Milano Centrale to Basel Sbbtrain Ec
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain 12 / ...
6h 32m€114–202Bus
- Take the bus from Milano, Autostazione Lampugnano to Karlsruhe central train stationbus N77
9h 45m€45–75Train to Milano Malpensa Airport, fly to Stuttgart Airport, train
- Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Stuttgart Airport (STR)plane MXP - STR
- Take the train from Stuttgart Hbf to Karlsruhe Hbftrain
5h 19m€85–269Fly Milan Linate Airport to Frankfurt, train
- Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane LIN - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
5h 39m€51–202Train to Milano Malpensa Airport, fly to Frankfurt, train
- Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane MXP - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
6h 1m€73–225Train to Milano Malpensa Airport, fly to Zurich Airport, train
- Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Zurich Airport (ZRH)plane MXP - ZRH
- Take the train from Zürich HB to Basel SBBtrain
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain
6h 28m€138–329
Milan to Karlsruhe by train (Trenitalia)
Comparing Your Travel Options
The cheapest way to get from Milan to Karlsruhe is to bus which costs €45 - €75 and takes 9h 45m.
The fastest way to get from Milan to Karlsruhe is to fly and train which takes 4h 47m and costs €120 - €370.
Yes, there is a direct bus departing from Milano, Autostazione Lampugnano and arriving at Karlsruhe central train station station. Services depart once daily, and operate every day. The journey takes approximately 9h 45m.
Yes, there is a direct train departing from Milano Centrale and arriving at Karlsruhe Hbf. Services depart twice daily, and operate every day. The journey takes approximately 6h 19m.
The distance between Milan and Karlsruhe is 531 km. The road distance is 528.3 km.
The best way to get from Milan to Karlsruhe without a car is to train which takes 6h 19m and costs €110 - €170.
The train from Milan Centrale to Karlsruhe Hbf takes 6h 19m including transfers and departs twice daily.
Milan to Karlsruhe bus services, operated by FlixBus, depart from Milano, Autostazione Lampugnano station.
Milan to Karlsruhe train services, operated by Trenitalia EuroCity, depart from Milano Centrale station.
The best way to get from Milan to Karlsruhe is to train which takes 6h 19m and costs €110 - €170. Alternatively, you can bus, which costs €45 - €75 and takes 9h 45m.
What companies run services between Milan, Italy and Karlsruhe, Germany?
Trenitalia EuroCity operates a train from Milano Centrale to Karlsruhe Hbf twice daily. Tickets cost €110–170 and the journey takes 6h 19m. Alternatively, FlixBus operates a bus from Milano, Autostazione Lampugnano to Karlsruhe central train station once daily. Tickets cost €45–75 and the journey takes 9h 45m.
- Website
- lufthansa.com
Flights from Milan Linate Airport to Stuttgart Airport via Munich
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- €130–310
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €50–400
Flights from Milan Linate Airport to Frankfurt via Munich
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- €50–340
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €75–340
Flights from Milano Malpensa Airport to Frankfurt via Munich
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €110–370
- Website
- airdolomiti.it
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €50–400
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €110–340
- Website
- swiss.com
Flights from Milano Malpensa Airport to Stuttgart Airport via Zurich Airport
- Ave. Duration
- 2h 45m
- When
- Tuesday to Sunday
- Estimated price
- €80–300
Flights from Milano Malpensa Airport to Frankfurt via Zurich Airport
- Ave. Duration
- 3h 20m
- When
- Monday to Saturday
- Estimated price
- €65–240
Flights from Milano Malpensa Airport to Zurich Airport
- Ave. Duration
- 58 min
- When
- Every day
- Estimated price
- €70–350
- Website
- eurowings.com
Flights from Milan Linate Airport to Stuttgart Airport
- Ave. Duration
- 1h
- When
- Thursday, Friday, and Sunday
- Estimated price
- €90–270
Flights from Milano Malpensa Airport to Stuttgart Airport
- Ave. Duration
- 1h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €75–190
- Website
- condor.com
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- €55–160
- Website
- easyjet.com
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–140
- Website
- ethiopianairlines.com
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Monday, Wednesday, Thursday, and Friday
- Estimated price
- €75–190
Flights from Milano Malpensa Airport to Zurich Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €95–160
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Milano Centrale to Karlsruhe Hbf
- Ave. Duration
- 6h 19m
- Frequency
- Twice daily
- Estimated price
- €110–170
- Website
- Trenitalia Eurocity
- 1st Class
- €110–170
- 2nd Class
- €110–150
Train from Milano Centrale to Basel Sbb
- Ave. Duration
- 4h 20m
- Frequency
- Every 2 hours
- Estimated price
- €75–130
- Website
- Trenitalia Eurocity
- 1st Class
- €90–130
- 2nd Class
- €75–110
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Zuerich Hb to Karlsruhe Hbf
- Ave. Duration
- 3h 15m
- Frequency
- 4 times a day
- Estimated price
- €24–93
- Website
- Nightjet
- Sleeper Carriage
- €88–93
- Couchette Carriage
- €55–65
- Seating Carriage
- €24–29
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Every 30 minutes
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Every 30 minutes
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg GmbH
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €15–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €35–75
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €15–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €24–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €24–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €35–75
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- €13–60
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- €13–60
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Train from Milano Porta Garibaldi to Malpensa Aeroporto T1
- Ave. Duration
- 43 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
Train from Milano Porta Garibaldi to Malpensa Aeroporto T1
- Ave. Duration
- 43 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
Train from Milano Porta Garibaldi to Malpensa Aeroporto T1
- Ave. Duration
- 43 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 53m
- Frequency
- Twice daily
- Estimated price
- €14–29
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 53m
- Frequency
- Twice daily
- Estimated price
- €14–29
- Website
- Nederlandse Spoorwegen (NS)
Train from Zürich HB to Basel SBB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €26–40
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Milano, Autostazione Lampugnano to Zürich
- Ave. Duration
- 3h 40m
- Frequency
- Every 4 hours
- Estimated price
- €18–30
- Website
- BlaBlaCar Bus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Karlsruhe central train station
- Ave. Duration
- 9h 45m
- Frequency
- Once daily
- Estimated price
- €45–75
- Website
- Flixbus
Want to know more about travelling around Germany
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Booking & Getting There
Milan to Karlsruhe bus services, operated by FlixBus, arrive at Karlsruhe central train station.
Milan to Karlsruhe train services, operated by Trenitalia EuroCity, arrive at Karlsruhe Hbf station.
Yes, the driving distance between Milan to Karlsruhe is 528 km. It takes approximately 5h 12m to drive from Milan to Karlsruhe.
Book your Milan to Karlsruhe train tickets online with Omio.
Book your Milan to Karlsruhe bus tickets online with Omio and FlixBus.
There are 899+ hotels available in Karlsruhe.












































