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How to get fromMilan to Karlsruheby train (Trenitalia), bus, car, train, plane, or night train

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There are 10 ways to get from Milan to Karlsruhe by train (Trenitalia), bus, car, train, plane, or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Milano Centrale to Karlsruhe Hbftrain train Ec
    6h 19m
    €110–170

  2. Bus

    cheapest
    1. Take the bus from Milano, Autostazione Lampugnano to Karlsruhe central train stationbus bus N77
    9h 55m
    €45–75

  3. Bus via Zurich

    1. Take the bus from Milano - Famagosta to ZÜRICH, Carparkplatz am Sihlquaibus bus
    2. Take the bus from Zurich Bus Station to Karlsruhe central train stationbus bus FlixBus 027 / ...
    7h 32m
    €83–116

  4. Drive  528.3 km

    1. Drive from Milan to Karlsruhecar car 528.3 km
    5h 12m
    €85–123

  5. Train to Milano Malpensa Airport, fly to Stuttgart Airport, train

    1. Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Stuttgart Airport (STR)plane plane MXP - STR
    3. Take the train from Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train
    5h 19m
    €87–284

  6. Train via Basel

    1. Take the train from Milano Centrale to Basel Sbbtrain train Ec
    2. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train 12 / ...
    6h 32m
    €114–197

  7. Train, night train

    1. Take the train from Milano Porta Garibaldi to Como S.Giovannitrain train S11
    2. Take the train from Como S. Giovanni to Zürich HBtrain train Ec
    3. Take the nighttrain from Zuerich Hb to Karlsruhe Hbfnighttrain night train Nj
    8h 46m
    €93–217

  8. Fly Milan Linate Airport to Frankfurt, train

    1. Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane plane LIN - FRA
    2. Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain train
    3. Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train
    5h 3m
    €50–238

  9. Train to Milano Malpensa Airport, fly to Frankfurt, train

    1. Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane plane MXP - FRA
    3. Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain train
    4. Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train
    5h 25m
    €77–261

  10. Train to Milano Malpensa Airport, fly to Zurich Airport, train

    1. Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Zurich Airport (ZRH)plane plane MXP - ZRH
    3. Take the train from Zürich HB to Basel SBBtrain train
    4. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train
    6h 28m
    €140–319

Milan to Karlsruhe by train (Trenitalia)

Calendar15Weekly Trains
Duration6h 19mAverage Duration
Ticket€110Cheapest Price
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Comparing Your Travel Options

Map of how to get from Milan to Karlsruhe.ExpandLaunch map view
  • Distance: 530.6 km
  • Duration: 6h 19m

What companies run services between Milan, Italy and Karlsruhe, Germany?

Trenitalia EuroCity operates a train from Milano Centrale to Karlsruhe Hbf twice daily. Tickets cost €110–170 and the journey takes 6h 19m. Alternatively, you can take a bus from Milano - Famagosta to Karlsruhe central train station via Zurich Bus Station in around 7h 32m.

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