There are 7 ways to get from Milan to Mesagne by plane, train (Trenitalia), bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Milan Linate Airport
best- Fly from Milan Linate Airport (LIN) to Brindisi Airport (BDS)plane LIN - BDS
4h 24m€59–184Train to Milano Malpensa Airport, fly
cheapest- Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Brindisi Airport (BDS)plane MXP - BDS
4h 56m€41–237Train (Trenitalia)
- Take the train from Milano Centrale to Brindisitrain Fr
8h 59m€105–228Bus
- Take the bus from Milano, San Donato M3 to Brindisibus 420
15h 53m€86–128Drive 992.9 km
- Drive from Milan to Mesagnecar 992.9 km
9h 14m€160–231Bus to Il Caravaggio International Airport, fly
- Take the bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airportbus
- Fly from Il Caravaggio International Airport (BGY) to Brindisi Airport (BDS)plane BGY - BDS
5h 3m€52–295Train via Bari
- Take the train from Milano Centrale to Bari Centraletrain 9939
- Take the train from Bari Centrale to Brindisitrain Fr / ...
10h 45m€137–227
Milan to Mesagne by bus and foot
Comparing Your Travel Options
The cheapest way to get from Milan to Mesagne is to train and fly which costs €40 - €240 and takes 4h 56m.
The fastest way to get from Milan to Mesagne is to fly which takes 4h 24m and costs €55 - €190.
No, there is no direct bus from Milan to Mesagne. However, there are services departing from Milano, San Donato M3 and arriving at Mesagne via Brindisi - v.le Porta Pia. The journey, including transfers, takes approximately 15h 53m.
No, there is no direct train from Milan to Mesagne. However, there are services departing from Milano Centrale and arriving at Brindisi via . The journey, including transfers, takes approximately 8h 59m.
The distance between Milan and Mesagne is 912 km. The road distance is 992.9 km.
The best way to get from Milan to Mesagne without a car is to train which takes 8h 59m and costs €100 - €230.
It takes approximately 4h 24m to get from Milan to Mesagne, including transfers.
Milan to Mesagne bus services, operated by FlixBus, depart from Milano, San Donato M3 station.
Milan to Mesagne train services, operated by Trenitalia Frecce, depart from Milano Centrale station.
The best way to get from Milan to Mesagne is to fly which takes 4h 24m and costs €55 - €190. Alternatively, you can train, which costs €100 - €230 and takes 8h 59m, you could also bus, which costs €85 - €130 and takes 15h 53m.
What companies run services between Milan, Italy and Mesagne, Italy?
easyJet and ITA Airways fly from Milan Linate Airport (LIN) to Brindisi Airport (BDS) every 4 hours. Alternatively, Trenitalia Frecce operates a train from Milano Centrale to Brindisi every 4 hours. Tickets cost €130–230 and the journey takes 7h 52m. Trenitalia Intercity also services this route every 4 hours.
- Website
- ryanair.com
Flights from Milano Malpensa Airport to Brindisi Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €45–220
Flights from Il Caravaggio International Airport to Brindisi Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €45–270
- Website
- easyjet.com
Flights from Milan Linate Airport to Brindisi Airport
- Ave. Duration
- 1h 40m
- When
- Monday and Thursday
- Estimated price
- €35–110
Flights from Milano Malpensa Airport to Brindisi Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- €29–210
- Website
- ita-airways.com
Flights from Milan Linate Airport to Brindisi Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €55–180
Flights from Milan Linate Airport to Brindisi Airport via Rome
- Ave. Duration
- 3h 38m
- When
- Every day
- Estimated price
- €55–180
- Website
- swiss.com
Flights from Milano Malpensa Airport to Brindisi Airport via Zurich
- Ave. Duration
- 4h 15m
- When
- Monday and Friday
- Estimated price
- €75–300
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Milano Centrale to Brindisi
- Ave. Duration
- 7h 52m
- Frequency
- Every 4 hours
- Estimated price
- €130–230
- Website
- Trenitalia Frecce
Train from Bari Centrale to Brindisi
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- €15–26
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Milano Centrale to Brindisi
- Ave. Duration
- 11h 8m
- Frequency
- Every 4 hours
- Estimated price
- €100–190
- Website
- Trenitalia Intercity
Train from Bari Centrale to Brindisi
- Ave. Duration
- 1h 14m
- Frequency
- Every 3 hours
- Estimated price
- €11–22
- Website
- Trenitalia Intercity
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Train from Milano Porta Garibaldi to Malpensa Aeroporto T1
- Ave. Duration
- 43 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Bari Centrale
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- €120–200
- Website
- Italo Treno
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Bari Centrale to Brindisi
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €13–19
- Website
- Trenitalia
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Milano, San Donato M3 to Brindisi
- Ave. Duration
- 14h 10m
- Frequency
- Twice daily
- Estimated price
- €85–130
- Website
- Flixbus
- [email protected]
- Website
- TERRAVISION
Bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airport
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–23
- Website
- TERRAVISION
- Phone
- 035.319366
- [email protected]
- Website
- orioshuttle.com
Bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airport
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- €11–15
- Schedules at
- orioshuttle.com
Want to know more about travelling around Italy
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Booking & Getting There
Milan to Mesagne bus services, operated by FlixBus, arrive at Brindisi station.
Milan to Mesagne train services, operated by Trenitalia Frecce, arrive at Brindisi station.
Yes, the driving distance between Milan to Mesagne is 993 km. It takes approximately 9h 14m to drive from Milan to Mesagne.
Book your Milan to Mesagne train tickets online with Omio.
Book your Milan to Mesagne bus tickets online with Omio.
There are 1587+ hotels available in Mesagne.


































