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How to get fromMilan to Sistine Chapelby train (Trenitalia), bus, car, plane, or train

Find Transport to Sistine Chapel

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There are 10 ways to get from Milan to Sistine Chapel by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Milano Centrale to Roma Terminitrain train Fr / ...
    3h 47m
    €72–171
  2. Bus

    cheapest
    1. Take the bus from Milano, San Donato M3 to Rome Tiburtina Largo Mazzonibus bus Bergamo
    8h 35m
    €38–77
  3. Drive 573.3 km

    1. Drive from Milan to Sistine Chapelcar car 573.3 km
    5h 19m
    €90–130
  4. Fly from Milan Linate Airport

    1. Fly from Milan Linate Airport (LIN) to Fiumicino International Airport (FCO)plane plane LIN - FCO
    3h 20m
    €55–168
  5. Train via Milano Centrale

    1. Take the train from Milano Centrale to Roma Terminitrain train 9995 / ...
    3h 48m
    €74–152
  6. Train via Milan Rogoredo

    1. Take the train from Milan Rogoredo to Roma Terminitrain train 9975 / ...
    4h 6m
    €71–145
  7. Train to Turin Caselle Airport, fly

    1. Take the train from Milano Centrale to Torino Porta di Susatrain train
    2. Fly from Turin Caselle Airport (TRN) to Fiumicino International Airport (FCO)plane plane TRN - FCO
    4h 34m
    €58–195
  8. Train to Genoa Cristoforo Colombo Airport, fly

    1. Take the train from Milano Rogoredo to Genova P.Za Principetrain train
    2. Fly from Genoa Cristoforo Colombo Airport (GOA) to Fiumicino International Airport (FCO)plane plane GOA - FCO
    5h 29m
    €62–199
  9. Train to Bologna Guglielmo Marconi Airport, fly

    1. Take the train from Milano Rogoredo to Bologna Centraletrain train
    2. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Fiumicino International Airport (FCO)plane plane BLQ - FCO
    4h 16m
    €65–195
  10. Train to Milano Malpensa Airport, fly

    1. Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Fiumicino International Airport (FCO)plane plane MXP - FCO
    3h 51m
    €47–161

Milan to Sistine Chapel by train, bus, and foot

Calendar416Weekly Services
Duration3h 47mAverage Duration
Ticket€72Cheapest Price
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Questions & Answers

What companies run services between Milan, Italy and Sistine Chapel, Vatican City?

Trenitalia Frecce operates a train from Milano Centrale to Roma Termini every 30 minutes. Tickets cost €80–170 and the journey takes 3h 4m. ItaloTreno also services this route once daily. Alternatively, Itabus S.p.A. operates a bus from Milano, San Donato M3 to Rome Tiburtina Largo Mazzoni once daily. Tickets cost €35–70 and the journey takes 7h 30m.

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Want to know more about travelling around Vatican City

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