There are 9 ways to get from Milan to Speyer by train (Trenitalia), bus, car, plane, train, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Milano Centrale to Karlsruhe Hbftrain Ec
- Take the train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOBtrain Re4
7h 34m€123–185Fly Milan Linate Airport to Frankfurt, train
cheapest- Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane LIN - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
5h 16m€55–209Bus
- Take the bus from Milano, Autostazione Lampugnano to Mannheim central bus stationbus N77
12h 49m€63–110Drive 573.7 km
- Drive from Milan to Speyercar 573.7 km
5h 36m€91–131Train via Basel
- Take the train from Milano Centrale to Basel Sbbtrain Ec
- Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain 12 / ...
7h 40m€129–339Train, night train
- Take the train from Milano Porta Garibaldi to Como S.Giovannitrain S11
- Take the train from Como S. Giovanni to Zürich HBtrain Ec
- Take the night train from Zuerich Hb to Bruchsalnighttrain Nj
- Take the train from Bruchsal to Speyer, Hbf/ZOBtrain S3 / ...
10h 47m€121–407Train to Milano Malpensa Airport, fly to Frankfurt, train
- Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane MXP - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
5h 37m€77–252Train to Milano Malpensa Airport, fly to Stuttgart Airport, train
- Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Stuttgart Airport (STR)plane MXP - STR
- Take the train from Hauptbahnhof to Mannheim, Hauptbahnhoftrain
6h 2m€90–270Train to Turin Caselle Airport, fly to Frankfurt, train
- Take the train from Milano Centrale to Torino Porta Susatrain
- Fly from Turin Caselle Airport (TRN) to Frankfurt (FRA)plane TRN - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
6h 29m€128–342
Milan to Speyer by train
Questions & Answers
The cheapest way to get from Milan to Speyer is to bus which costs €60 - €110 and takes 12h 49m.
The fastest way to get from Milan to Speyer is to fly and train which takes 5h 16m and costs €55 - €210.
No, there is no direct bus from Milan to Speyer. However, there are services departing from Milano, Autostazione Lampugnano and arriving at Speyer, Hbf/ZOB via Ludwigsh., B. Pl. Bf LU Mitte. The journey, including transfers, takes approximately 12h 49m.
No, there is no direct train from Milan to Speyer. However, there are services departing from Milano Centrale and arriving at Speyer, Hbf/ZOB via Karlsruhe Hauptbahnhof. The journey, including transfers, takes approximately 7h 34m.
The distance between Milan and Speyer is 582 km. The road distance is 573.7 km.
The best way to get from Milan to Speyer without a car is to train which takes 7h 34m and costs €120 - €190.
It takes approximately 7h 34m to get from Milan to Speyer, including transfers.
Milan to Speyer bus services, operated by FlixBus, depart from Milano, Autostazione Lampugnano station.
Milan to Speyer train services, operated by Trenitalia EuroCity, depart from Milano Centrale station.
The best way to get from Milan to Speyer is to train which takes 7h 34m and costs €120 - €190. Alternatively, you can bus, which costs €60 - €110 and takes 12h 49m.
What companies run services between Milan, Italy and Speyer, Germany?
You can take a train from Milano Centrale to Speyer, Hbf/ZOB via Karlsruhe Hbf and Karlsruhe Hauptbahnhof in around 7h 34m. Alternatively, FlixBus operates a bus from Milano, Autostazione Lampugnano to Mannheim central bus station once daily. Tickets cost €55–95 and the journey takes 11h.
- Website
- lufthansa.com
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €50–450
Flights from Milan Linate Airport to Frankfurt via Munich
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €50–250
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €70–370
Flights from Milano Malpensa Airport to Frankfurt via Munich
- Ave. Duration
- 3h 7m
- When
- Every day
- Estimated price
- €70–450
Flights from Turin Caselle Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €95–480
Flights from Turin Caselle Airport to Frankfurt via Munich
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- €95–600
- Website
- airdolomiti.it
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €50–450
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €90–370
Flights from Turin Caselle Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Tuesday to Friday
- Estimated price
- €110–480
- Website
- condor.com
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- €55–170
- Website
- easyjet.com
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–130
- Website
- swiss.com
Flights from Milano Malpensa Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 20m
- When
- Monday to Saturday
- Estimated price
- €70–240
Flights from Milano Malpensa Airport to Stuttgart Airport via Zurich
- Ave. Duration
- 2h 45m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €90–290
- Website
- eurowings.com
Flights from Milano Malpensa Airport to Stuttgart Airport
- Ave. Duration
- 1h
- When
- Monday and Friday
- Estimated price
- €85–160
- Phone
- +39 06 68475475
- [email protected]
- Website
- trenitalia.com
Train from Milano Centrale to Karlsruhe Hbf
- Ave. Duration
- 6h 19m
- Frequency
- Twice daily
- Estimated price
- €110–170
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €110–170
- 2nd Class
- €110–150
Train from Milano Centrale to Basel Sbb
- Ave. Duration
- 4h 20m
- Frequency
- Every 3 hours
- Estimated price
- €75–130
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €90–130
- 2nd Class
- €75–110
Train from Basel SBB to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 12m
- Frequency
- Twice daily
- Estimated price
- €55–110
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €75–110
- 2nd Class
- €55–80
- Phone
- +49 621 830 1200
- Website
- suewex.de
Train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOB
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- €12–17
- Schedules at
- suewex.de
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOB
- Ave. Duration
- 1h 36m
- Frequency
- Hourly
- Estimated price
- €12–21
- Website
- https://int.bahn.de/en
Train from Bruchsal to Speyer, Hbf/ZOB
- Ave. Duration
- 1h 22m
- Frequency
- Hourly
- Estimated price
- €17–29
- Website
- https://int.bahn.de/en
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €13–55
- Website
- https://int.bahn.de/en
Train from Basel SBB to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 6m
- Frequency
- Hourly
- Estimated price
- €45–200
- Website
- https://int.bahn.de/en
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €13–55
- Website
- https://int.bahn.de/en
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Every 30 minutes
- Estimated price
- €19–85
- Website
- https://int.bahn.de/en
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €13–55
- Website
- https://int.bahn.de/en
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 32 min
- Frequency
- 5 times a day
- Estimated price
- €8–17
- Website
- https://www.ns.nl/en
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 32 min
- Frequency
- 5 times a day
- Estimated price
- €8–17
- Website
- https://www.ns.nl/en
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Once daily
- Estimated price
- €12–25
- Website
- https://www.ns.nl/en
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 32 min
- Frequency
- 5 times a day
- Estimated price
- €8–17
- Website
- https://www.ns.nl/en
- Phone
- +43 5 1717
- Website
- konzern.oebb.at
Train from Basel SBB to Mannheim, Hauptbahnhof
- Ave. Duration
- 3h 3m
- Frequency
- Twice a week
- Estimated price
- €55–85
- Website
- https://konzern.oebb.at/en/
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- trenord.it
Train from Milano Porta Garibaldi to Como S.Giovanni
- Ave. Duration
- 1h 1m
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
Train from Milano Porta Garibaldi to Malpensa Aeroporto T1
- Ave. Duration
- 43 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
Train from Milano Porta Garibaldi to Malpensa Aeroporto T1
- Ave. Duration
- 43 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Milano Porta Garibaldi to Como S.Giovanni
- Ave. Duration
- 1h 1m
- Frequency
- Once daily
- Estimated price
- €17–55
- Website
- https://www.sbb.ch/en
Train from Como S. Giovanni to Zürich HB
- Ave. Duration
- 2h 36m
- Frequency
- Hourly
- Estimated price
- €75–230
- Website
- https://www.sbb.ch/en
- Phone
- +43 (0) 51717
- Website
- nightjet.com
Night train from Zuerich Hb to Bruchsal
- Ave. Duration
- 3h 33m
- Frequency
- Twice daily
- Estimated price
- €25–94
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €90–94
- Couchette Carriage
- €55–70
- Seating Carriage
- €25–30
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Torino Porta Susa
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €21–45
- Schedules at
- trenitalia.com
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Milano Centrale to Torino Porta Susa
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- €17–29
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Torino Porta Susa
- Ave. Duration
- 1h 1m
- Frequency
- Twice daily
- Estimated price
- €18–35
- Website
- https://www.italotreno.it/en
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Milano, Autostazione Lampugnano to Mannheim central bus station
- Ave. Duration
- 11h
- Frequency
- Once daily
- Estimated price
- €55–95
- Website
- https://www.flixbus.co.uk
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More Questions & Answers
Milan to Speyer bus services, operated by FlixBus, arrive at Mannheim central bus station.
Milan to Speyer train services, operated by Trenitalia EuroCity, arrive at Karlsruhe Hbf station.
Yes, the driving distance between Milan to Speyer is 574 km. It takes approximately 5h 36m to drive from Milan to Speyer.
Book your Milan to Speyer train tickets online with Omio.
There are 1498+ hotels available in Speyer.


















































