There are 10 ways to get from Milan to Speyer by train (Trenitalia), bus, car, plane, train, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Basel
best- Take the train from Milano Centrale to Basel Sbbtrain Ec
- Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain 12 / ...
7h 40m€127–254Fly Milan Linate Airport to Frankfurt, train
cheapest- Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane LIN - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
5h 15m€47–196Bus
- Take the bus from Milano, Autostazione Lampugnano to Mannheim central bus stationbus N77
12h 39m€55–90Drive 573.7 km
- Drive from Milan to Speyercar 573.7 km
5h 36m€93–135Train
- Take the train from Milano Centrale to Karlsruhe Hbftrain Ec
- Take the train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOBtrain S3 / ...
8h 21m€126–234Bus, night train, train
- Take the bus from Milano, Autostazione Lampugnano to Zürichbus
- Take the nighttrain from Zuerich Hb to Karlsruhe Hbfnighttrain Nj
- Take the train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOBtrain S3 / ...
10h 6m€57–195Train to Milano Malpensa Airport, fly to Frankfurt, train
- Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane MXP - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
5h 37m€69–219Fly Milan Linate Airport to Stuttgart Airport, train
- Fly from Milan Linate Airport (LIN) to Stuttgart Airport (STR)plane LIN - STR
- Take the train from Hauptbahnhof to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Speyer, Hbf/ZOBtrain
5h 27m€129–363Train to Milano Malpensa Airport, fly to Stuttgart Airport, train
- Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Stuttgart Airport (STR)plane MXP - STR
- Take the train from Hauptbahnhof to Mannheim, Hauptbahnhoftrain
5h 59m€86–266Train to Turin Caselle Airport, fly to Frankfurt, train
- Take the train from Milano Centrale to Torino Porta di Susatrain
- Fly from Turin Caselle Airport (TRN) to Frankfurt (FRA)plane TRN - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
6h 30m€119–344
Milan to Speyer by train
Comparing Your Travel Options
The cheapest way to get from Milan to Speyer is to bus which costs €55 - €90 and takes 12h 39m.
The fastest way to get from Milan to Speyer is to fly and train which takes 5h 15m and costs €45 - €200.
No, there is no direct bus from Milan to Speyer. However, there are services departing from Milano, Autostazione Lampugnano and arriving at Speyer, Hbf/ZOB via Ludwigsh., B. Pl. Bf LU Mitte. The journey, including transfers, takes approximately 12h 39m.
No, there is no direct train from Milan to Speyer. However, there are services departing from Milano Centrale and arriving at Speyer, Hbf/ZOB via Basel SBB and Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 7h 40m.
The distance between Milan and Speyer is 638 km. The road distance is 573.7 km.
The best way to get from Milan to Speyer without a car is to train via Basel which takes 7h 40m and costs €120 - €260.
It takes approximately 7h 40m to get from Milan to Speyer, including transfers.
Milan to Speyer bus services, operated by FlixBus, depart from Milano, Autostazione Lampugnano station.
Milan to Speyer train services, operated by Trenitalia EuroCity, depart from Milano Centrale station.
The best way to get from Milan to Speyer is to train via Basel which takes 7h 40m and costs €120 - €260. Alternatively, you can bus, which costs €55 - €90 and takes 12h 39m.
What companies run services between Milan, Italy and Speyer, Germany?
You can take a train from Milano Centrale to Speyer, Hbf/ZOB via Basel SBB and Mannheim, Hauptbahnhof in around 7h 40m. Alternatively, FlixBus operates a bus from Milano, Autostazione Lampugnano to Mannheim central bus station once daily. Tickets cost €50–85 and the journey takes 10h 50m.
- Website
- lufthansa.com
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €55–400
Flights from Milan Linate Airport to Frankfurt via Munich
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- €50–350
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €75–340
Flights from Milano Malpensa Airport to Frankfurt via Munich
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €110–370
Flights from Milan Linate Airport to Stuttgart Airport via Munich
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- €130–310
Flights from Turin Caselle Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €110–430
Flights from Turin Caselle Airport to Frankfurt via Munich
- Ave. Duration
- 3h 22m
- When
- Monday to Saturday
- Estimated price
- €110–460
- Website
- airdolomiti.it
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €55–400
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €110–340
Flights from Turin Caselle Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €130–420
- Website
- condor.com
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- €55–160
- Website
- eurowings.com
Flights from Milan Linate Airport to Stuttgart Airport
- Ave. Duration
- 1h
- When
- Thursday, Friday, and Sunday
- Estimated price
- €90–270
Flights from Milano Malpensa Airport to Stuttgart Airport
- Ave. Duration
- 1h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €80–190
- Website
- easyjet.com
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–140
- Website
- swiss.com
Flights from Milano Malpensa Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 20m
- When
- Monday to Saturday
- Estimated price
- €65–250
Flights from Milano Malpensa Airport to Stuttgart Airport via Zurich
- Ave. Duration
- 2h 45m
- When
- Tuesday to Sunday
- Estimated price
- €80–300
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Milano Centrale to Basel Sbb
- Ave. Duration
- 4h 20m
- Frequency
- Every 2 hours
- Estimated price
- €75–130
- Website
- Trenitalia Eurocity
- 1st Class
- €90–130
- 2nd Class
- €75–110
Train from Basel SBB to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 12m
- Frequency
- Twice daily
- Estimated price
- €55–110
- Website
- Trenitalia Eurocity
- 1st Class
- €75–110
- 2nd Class
- €55–80
Train from Milano Centrale to Karlsruhe Hbf
- Ave. Duration
- 6h 19m
- Frequency
- Twice daily
- Estimated price
- €110–170
- Website
- Trenitalia Eurocity
- 1st Class
- €110–170
- 2nd Class
- €110–150
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 6m
- Frequency
- Hourly
- Estimated price
- €45–95
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €13–27
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €13–27
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €20–40
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €20–40
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €13–27
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 32 min
- Frequency
- 4 times a day
- Estimated price
- €7–16
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 32 min
- Frequency
- 4 times a day
- Estimated price
- €7–16
- Website
- Nederlandse Spoorwegen (NS)
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Once daily
- Estimated price
- €11–24
- Website
- Nederlandse Spoorwegen (NS)
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Once daily
- Estimated price
- €11–24
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 32 min
- Frequency
- 4 times a day
- Estimated price
- €7–16
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOB
- Ave. Duration
- 1h 36m
- Frequency
- Hourly
- Estimated price
- €15–70
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOB
- Ave. Duration
- 1h 36m
- Frequency
- Hourly
- Estimated price
- €15–70
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mannheim, Hauptbahnhof to Speyer, Hbf/ZOB
- Ave. Duration
- 28 min
- Frequency
- Hourly
- Estimated price
- €3–17
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOB
- Ave. Duration
- 40 min
- Frequency
- Twice daily
- Estimated price
- €17–25
- Schedules at
- Süwex
Train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOB
- Ave. Duration
- 40 min
- Frequency
- Twice daily
- Estimated price
- €17–25
- Schedules at
- Süwex
Train from Mannheim, Hauptbahnhof to Speyer, Hbf/ZOB
- Ave. Duration
- 25 min
- Frequency
- 5 times a week
- Estimated price
- €8–12
- Schedules at
- Süwex
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Zuerich Hb to Karlsruhe Hbf
- Ave. Duration
- 3h 15m
- Frequency
- 4 times a day
- Estimated price
- €24–93
- Website
- Nightjet
- Sleeper Carriage
- €88–93
- Couchette Carriage
- €55–65
- Seating Carriage
- €24–29
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Train from Milano Porta Garibaldi to Malpensa Aeroporto T1
- Ave. Duration
- 43 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
Train from Milano Porta Garibaldi to Malpensa Aeroporto T1
- Ave. Duration
- 43 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Torino Porta di Susa
- Ave. Duration
- 48 min
- Frequency
- Every 2 hours
- Estimated price
- €16–27
- Website
- Italo Treno
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Milano, Autostazione Lampugnano to Mannheim central bus station
- Ave. Duration
- 10h 50m
- Frequency
- Once daily
- Estimated price
- €50–85
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Milano, Autostazione Lampugnano to Zürich
- Ave. Duration
- 3h 40m
- Frequency
- Every 4 hours
- Estimated price
- €18–30
- Website
- BlaBlaCar Bus
Want to know more about travelling around Germany
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Booking & Getting There
Milan to Speyer bus services, operated by FlixBus, arrive at Mannheim central bus station.
Milan to Speyer train services, operated by Trenitalia EuroCity, arrive at Basel Sbb station.
Yes, the driving distance between Milan to Speyer is 574 km. It takes approximately 5h 36m to drive from Milan to Speyer.
Book your Milan to Speyer train tickets online with Omio.
There are 1485+ hotels available in Speyer.













































