There are 11 ways to get from Milan to Syracuse by plane, bus, train, ferry, car, car ferry, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Milan Linate Airport to Catania–Fontanarossa Airport, bus
best- Fly from Milan Linate Airport (LIN) to Catania–Fontanarossa Airport (CTA)plane LIN - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
4h 13m€49–190Train to Milano Malpensa Airport, fly to Catania–Fontanarossa Airport, bus
cheapest- Take the train from Milano Porta Garibaldi to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Catania–Fontanarossa Airport (CTA)plane MXP - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
4h 45m€23–183Train, ferry
- Take the train from Milano Centrale to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Siracusatrain Re
12h 41mBus
- Take the bus from Milano - Famagosta to Catania Central Bus Stationbus
- Take the bus from Catania Via Archimede to Siracusa - Von Platenbus Catania
19h 20m€180–248Drive, car ferry
- Drive from Milan to Port of Genoacar
- Take the carferry from Port of Genoa to Port of Palermocarferry
- Drive from Port of Palermo to Syracusecar
25h 29m€163–243Bus to Il Caravaggio International Airport, fly to Catania–Fontanarossa Airport, bus
- Take the bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airportbus
- Fly from Il Caravaggio International Airport (BGY) to Catania–Fontanarossa Airport (CTA)plane BGY - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
4h 57m€42–251Train to Turin Caselle Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Milano Centrale to Torino Porta di Susatrain
- Fly from Turin Caselle Airport (TRN) to Catania–Fontanarossa Airport (CTA)plane TRN - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
5h 13m€40–228Fly Milan Linate Airport to Vincenzo Magliocco Airport, train
- Fly from Milan Linate Airport (LIN) to Vincenzo Magliocco Airport (CIY)plane LIN - CIY
- Take the train from Comiso to Siracusatrain
6h 55m€116–591Train to Verona Villafranca Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Milano Centrale to Verona Porta Nuovatrain
- Fly from Verona Villafranca Airport (VRN) to Catania–Fontanarossa Airport (CTA)plane VRN - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
5h 44m€50–316Bus via Milano, San Donato M3
- Take the bus from Milano, San Donato M3 to Catania Airportbus N528
- Take the bus from Catania Airport to Siracusa - Von Platenbus Catania
22h 16m€118–181Night train
- Take the nighttrain from Milano Centrale to Siracusanighttrain Ini
19h 38m€120–210
Milan Linate Airport (LIN) to Catania–Fontanarossa Airport (CTA) flights
Comparing Your Travel Options
The cheapest way to get from Milan to Syracuse is to train and fly and bus which costs €23 - €190 and takes 4h 45m.
The fastest way to get from Milan to Syracuse is to fly and bus which takes 4h 13m and costs €45 - €190.
No, there is no direct bus from Milan to Syracuse. However, there are services departing from Milano - Famagosta and arriving at Siracusa - Von Platen via Catania Via Archimede. The journey, including transfers, takes approximately 19h 20m.
Yes, there is an overnight train departing from Milano Centrale and arriving at Siracusa. This train operates every day. The journey takes approximately 19h 38m.
The distance between Milan and Syracuse is 1076 km.
The best way to get from Milan to Syracuse without a car is to train and ferry which takes 12h 41m and costs .
It takes approximately 4h 13m to get from Milan to Syracuse, including transfers.
Milan to Syracuse bus services, operated by Onebus, depart from Milano - Famagosta station.
Milan to Syracuse train services, operated by Trenitalia Intercity Night, depart from Milano Centrale station.
Milan to Syracuse bus services, operated by Onebus, arrive at Catania Central Bus Station.
What companies run services between Milan, Italy and Syracuse, Italy?
You can take a bus from Milano - Famagosta to Siracusa - Von Platen via Catania Central Bus Station and Catania Via Archimede in around 19h 20m. Alternatively, Trenitalia Intercity Night operates a vehicle from Milano Centrale to Siracusa twice daily. Tickets cost €120–210 and the journey takes 19h 38m.
- Website
- ryanair.com
Flights from Milano Malpensa Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €50–170
Flights from Milano Malpensa Airport to Catania–Fontanarossa Airport via Naples
- Ave. Duration
- 4h 15m
- When
- Wednesday and Thursday
- Estimated price
- €50–170
Flights from Il Caravaggio International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €45–220
Flights from Turin Caselle Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- €30–240
Flights from Verona Villafranca Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €55–270
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Milano Centrale to Villa S.Giovanni
- Ave. Duration
- 8h 21m
- Frequency
- Every 4 hours
- Estimated price
- €160–290
- Website
- Trenitalia Frecce
Train from Milano Centrale to Verona Porta Nuova
- Ave. Duration
- 1h 13m
- Frequency
- Every 30 minutes
- Estimated price
- €20–35
- Website
- Trenitalia Frecce
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - Von Platen
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €3–9
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - Von Platen
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
Want to know more about travelling around Italy
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Booking & Getting There
Milan to Syracuse train services, operated by Trenitalia Intercity Night, arrive at Siracusa station.
Book your Milan to Syracuse bus tickets online with Omio.
There are 3108+ hotels available in Syracuse.







