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How to get fromMilano Centrale Station to Iserniaby train (Trenitalia), train, bus, car, or plane

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There are 11 ways to get from Milano Centrale Station to Isernia by train (Trenitalia), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Milano Centrale to Roma Terminitrain train Fr / ...
    2. Take the train from Roma Termini to Iserniatrain train Re
    6h 12m
    €95–202

  2. Train to Milano Malpensa Airport, fly to Naples Airport, train

    cheapest
    1. Take the train from Milano Centrale to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Naples Airport (NAP)plane plane MXP - NAP
    3. Take the train from Caserta to Iserniatrain train
    7h
    €35–158

  3. Train, bus

    1. Take the train from Milano Centrale to Bologna centraletrain train 9941 / ...
    2. Take the bus from Bologna Centrale to Iserniabus bus 433
    10h 39m
    €72–133

  4. Drive 725.6 km

    1. Drive from Milano Centrale Station to Iserniacar car 725.6 km
    6h 42m
    €114–164

  5. Fly Milan Linate Airport to Fiumicino International Airport, train

    1. Fly from Milan Linate Airport (LIN) to Fiumicino International Airport (FCO)plane plane LIN - FCO
    2. Take the train from Roma Termini to Iserniatrain train
    6h 24m
    €80–212

  6. Bus

    1. Take the bus from Milano - Famagosta to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus bus 510 / ...
    3. Take the bus from Roma, Autostazione Tiburtina to Iserniabus bus
    11h 13m

  7. Fly Milan Linate Airport to Naples Airport, train

    1. Fly from Milan Linate Airport (LIN) to Naples Airport (NAP)plane plane LIN - NAP
    2. Take the train from Caserta to Iserniatrain train
    6h 27m
    €66–198

  8. Fly Milan Linate Airport to Foggia Gino Lisa Airport, bus

    1. Fly from Milan Linate Airport (LIN) to Foggia Gino Lisa Airport (FOG)plane plane LIN - FOG
    2. Take the bus from Foggia to Iserniabus bus
    6h 50m
    €86–299

  9. Bus to Il Caravaggio International Airport, fly to Naples Airport, train

    1. Take the bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airportbus bus
    2. Fly from Il Caravaggio International Airport (BGY) to Naples Airport (NAP)plane plane BGY - NAP
    3. Take the train from Caserta to Iserniatrain train
    7h 2m
    €53–198

  10. Train to Milano Malpensa Airport, fly to Abruzzo Airport, bus

    1. Take the train from Milano Centrale to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Abruzzo Airport (PSR)plane plane MXP - PSR
    3. Take the bus from Pescara to Iserniabus bus
    8h 14m
    €39–179

  11. Train to Milano Malpensa Airport, fly to Salerno Costa D'Amalfi Airport, train

    1. Take the train from Milano Centrale to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Salerno Costa D'Amalfi Airport (QSR)plane plane MXP - QSR
    3. Take the train from Salerno to Casertatrain train
    4. Take the train from Caserta to Iserniatrain train
    8h 54m
    €51–203

Milano Centrale Station to Isernia by train

Calendar70Weekly Trains
Duration6h 12mAverage Duration
Ticket€95Cheapest Price
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Questions & Answers

Map of how to get from Milano Centrale Station to Isernia.ExpandLaunch map view
  • Distance: 747.2 km
  • Duration: 6h 12m

What companies run services between Milano Centrale Station, Italy and Isernia, Italy?

You can take a train from Milano Centrale to Isernia via Roma Termini in around 6h 12m. Alternatively, you can take a bus from Milano, Stazione Centrale to Isernia via famagosta m2, Milano - Famagosta, Florence Villa Constanza Bus Station, and Roma, Autostazione Tiburtina in around 11h 13m.

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