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How to get fromMilano Centrale Station to Karlsruheby train (Trenitalia), bus, train, night train, car, or plane

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There are 11 ways to get from Milano Centrale Station to Karlsruhe by train (Trenitalia), bus, train, night train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Milano Centrale to Karlsruhe Hbftrain train Ec
    6h 19m
    €110–170
  2. Bus

    cheapest
    1. Take the bus from Milan to Karlsruhe central train stationbus bus FlixBus N487 / ...
    8h 53m
    €43–79
  3. Train, night train

    1. Take the train from Milano Centrale to Luganotrain train
    2. Take the train from Lugano to Zürich HBtrain train Ic2 / ...
    3. Take the nighttrain from Zuerich Hb to Karlsruhe Hbfnighttrain night train Nj
    7h 50m
    €90–292
  4. Drive 528.4 km

    1. Drive from Milano Centrale Station to Karlsruhecar car 528.4 km
    5h 12m
    €82–119
  5. Train via Basel

    1. Take the train from Milano Centrale to Basel Sbbtrain train Ec
    2. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train 12 / ...
    6h 29m
    €114–287
  6. Train to Milano Malpensa Airport, fly to Stuttgart Airport, train

    1. Take the train from Milano Centrale to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Stuttgart Airport (STR)plane plane MXP - STR
    3. Take the train from Stuttgart Hbf to Karlsruhe Hbftrain train
    5h 30m
    €87–248
  7. Fly Milan Linate Airport to Frankfurt, train

    1. Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane plane LIN - FRA
    2. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    5h 57m
    €57–255
  8. Train to Zurich Airport, fly to Stuttgart Airport, train

    1. Take the train from Milano Centrale to Zuerich Hbtrain train
    2. Fly from Zurich Airport (ZRH) to Stuttgart Airport (STR)plane plane ZRH - STR
    3. Take the train from Stuttgart Hbf to Karlsruhe Hbftrain train
    6h 53m
    €178–457
  9. Train to Milano Malpensa Airport, fly to Frankfurt, train

    1. Take the train from Milano Centrale to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane plane MXP - FRA
    3. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    6h 11m
    €73–295
  10. Train to Milano Malpensa Airport, fly to Zurich Airport, train

    1. Take the train from Milano Centrale to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Zurich Airport (ZRH)plane plane MXP - ZRH
    3. Take the train from Zürich HB to Basel SBBtrain train
    4. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train
    6h 35m
    €137–441
  11. Fly Milan Linate Airport to Munich International Airport, train

    1. Fly from Milan Linate Airport (LIN) to Munich International Airport (MUC)plane plane LIN - MUC
    2. Take the train from München Hbf to Hauptbahnhoftrain train
    3. Take the train from Stuttgart Hbf to Karlsruhe Hbftrain train
    7h 36m
    €137–516

Milano Centrale Station to Karlsruhe by train (Trenitalia)

Calendar16Weekly Trains
Duration6h 19mAverage Duration
Ticket€110Cheapest Price
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Questions & Answers

What companies run services between Milano Centrale Station, Italy and Karlsruhe, Germany?

Trenitalia EuroCity operates a train from Milano Centrale to Karlsruhe Hbf twice daily. Tickets cost €110–170 and the journey takes 6h 19m. Alternatively, FlixBus operates a bus from Milan to Karlsruhe central train station 5 times a day. Tickets cost €40–75 and the journey takes 7h 20m.

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