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How to get fromMilano Centrale Station to Mainzby plane, train (Trenitalia), bus, car, train, or night train

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There are 9 ways to get from Milano Centrale Station to Mainz by plane, train (Trenitalia), bus, car, train, or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Milan Linate Airport

    best
    1. Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane plane LIN - FRA
    4h 23m
    €49–158

  2. Train via Basel

    1. Take the train from Milano Centrale to Basel Sbbtrain train Ec
    2. Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain train 12 / ...
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train 55 / ...
    7h 45m
    €136–382

  3. Bus

    1. Take the bus from Milan to Mainz central train stationbus bus FlixBus 476
    13h 48m
    €68–114

  4. Drive 662.1 km

    1. Drive from Milano Centrale Station to Mainzcar car 662.1 km
    6h 13m
    €104–150

  5. Train to Milano Malpensa Airport, fly

    1. Take the train from Milano Centrale to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane plane MXP - FRA
    4h 36m
    €65–198

  6. Train to Turin Caselle Airport, fly

    1. Take the train from Milano Centrale to Torino Porta di Susatrain train
    2. Fly from Turin Caselle Airport (TRN) to Frankfurt (FRA)plane plane TRN - FRA
    5h 18m
    €121–292

  7. Train to Verona Villafranca Airport, fly

    1. Take the train from Milano Centrale to Verona Porta Nuovatrain train
    2. Fly from Verona Villafranca Airport (VRN) to Frankfurt (FRA)plane plane VRN - FRA
    5h 40m
    €144–371

  8. Train

    1. Take the train from Milano Centrale to Mannheim Hbftrain train Ec
    2. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    8h 28m
    €137–204

  9. Train, night train

    1. Take the train from Milano Centrale to Luganotrain train
    2. Take the train from Lugano to Zürich HBtrain train Ic2 / ...
    3. Take the night train from Zuerich Hb to Mannheim Hbfnighttrain night train Nj
    4. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    10h 34m
    €106–330

Milano Centrale Station to Mainz by train

Calendar73Weekly Trains
Duration7h 45mAverage Duration
Ticket€136Cheapest Price
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Questions & Answers

Map of how to get from Milano Centrale Station to Mainz.ExpandLaunch map view
  • Distance: 548.5 km
  • Duration: 4h 23m

What companies run services between Milano Centrale Station, Italy and Mainz, Germany?

easyJet, Lufthansa, and two other airlines fly from Milan Linate Airport (LIN) to Frankfurt (FRA) every 3 hours. Alternatively, you can take a train from Milano Centrale to Mainz, Hauptbahnhof via Basel SBB and Mannheim, Hauptbahnhof in around 7h 45m.

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