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How to get fromMillbrae to San Diegoby plane, train, bus, train (Amtrak), car, subway, or bus (Flixbus)

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There are 7 ways to get from Millbrae to San Diego by plane, train, bus, train (Amtrak), car, subway, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from San Francisco International Airport

    best
    1. Fly from San Francisco International Airport (SFO) to San Diego International Airport (SAN)plane plane SFO - SAN
    2h 39m
    $63–230

  2. Caltrain, bus

    1. Take the train from Millbrae Caltrain Southbound to San Jose Diridon Caltrain Southboundtrain train Local Weekday / ...
    2. Take the bus from San Jose Diridon Station to San Diego Greyhound Bus Stopbus bus Greyhound US0831
    13h 29m
    $88–139

  3. Caltrain, train

    1. Take the train from Millbrae Caltrain Southbound to San Jose Diridon Caltrain Southboundtrain train
    2. Take the train from San Jose to Los Angelestrain train
    3. Take the train from Los Angeles to San Diegotrain train
    16h 33m
    $308–479

  4. Drive  492.8 mi

    1. Drive from Millbrae to San Diegocar car 492.8 mi
    8h 21m
    $90–130

  5. BART to Oakland International Airport, fly

    1. Take the subway from Daly City to Coliseumsubway subway
    2. Fly from Oakland International Airport (OAK) to San Diego International Airport (SAN)plane plane OAK - SAN
    3h 48m
    $75–301

  6. Caltrain to Norman Y. Mineta San José International Airport, fly

    1. Take the train from Millbrae Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to San Diego International Airport (SAN)plane plane SJC - SAN
    3h 42m
    $80–492

  7. Bus (Flixbus)

    1. Take the bus from San Francisco to San Diegobus bus FlixBus N2003
    13h 54m
    $79–124

Millbrae to San Diego by train, bus, and tram

Calendar7Weekly Services
Duration13h 29mAverage Duration
Ticket$88Cheapest Price
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Comparing Your Travel Options

Map of how to get from Millbrae to San Diego.ExpandLaunch map view
  • Distance: 448.7 mi
  • Duration: 2h 39m

What companies run services between Millbrae, CA, USA and San Diego, CA, USA?

Frontier Airlines, Alaska Airlines, Inc., and two other airlines fly from San Francisco International Airport (SFO) to San Diego International Airport (SAN) hourly. Alternatively, you can take a train from Millbrae Caltrain Southbound to San Diego via San Jose Diridon Caltrain Southbound, San Jose, and Los Angeles in around 16h 33m.

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