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How to get fromMillsboro to Charlestonby taxi, plane, bus, train, or car

Find Transport to Charleston

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There are 3 ways to get from Millsboro to Charleston by taxi, plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, fly

    best
    1. Take the taxi from Millsboro to Salisbury–Ocean City–Wicomico Regional Airport (SBY)taxi taxi
    2. Fly from Salisbury–Ocean City–Wicomico Regional Airport (SBY) to Charleston International Airport (CHS)plane plane SBY - CHS
    6h 32m
    $157–492

  2. Drive 544.3 mi

    cheapest
    1. Drive from Millsboro to Charlestoncar car 544.3 mi
    11h 15m
    $100–144

  3. Bus, train

    1. Take the bus from Rehoboth P-N-R @ Country Club Rd to Wilmington Tcbus bus 305
    2. Take the train from Wilmington to Charleston Amtrak Stationtrain train Silver Meteor / ...
    17h 15m
    $227–460

Salisbury–Ocean City–Wicomico Regional Airport (SBY) to Charleston International Airport (CHS) flights

Calendar26Weekly Planes
Duration5h 8mAverage Duration
Ticket$71Cheapest Price
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Questions & Answers

Map of how to get from Millsboro to Charleston.ExpandLaunch map view
  • Distance: 493.7 mi
  • Duration: 6h 32m

What companies run services between Millsboro, DE, USA and Charleston, SC, USA?

There is no direct connection from Millsboro to Charleston. However, you can take the taxi to Salisbury–Ocean City–Wicomico Regional Airport (SBY) airport, fly to Charleston International Airport (CHS), walk to Charleston International Airport, then take the line 11 bus to Transit Mall. Alternatively, you can take a bus from Railroad St @ Central Alley to Charleston via Rehoboth P-N-R @ Country Club Rd, Wilmington Tc, Wilmington, and Charleston Amtrak Station in around 17h 15m.

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