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How to get fromMillsboro to Knoxvilleby taxi, plane, bus, train, or car

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There are 5 ways to get from Millsboro to Knoxville by taxi, plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, fly

    best
    1. Take the taxi from Millsboro to Salisbury–Ocean City–Wicomico Regional Airport (SBY)taxi taxi
    2. Fly from Salisbury–Ocean City–Wicomico Regional Airport (SBY) to Mcghee Tyson Airport (TYS)plane plane SBY - TYS
    4h 58m
    $260–870

  2. Drive 585.3 mi

    cheapest
    1. Drive from Millsboro to Knoxvillecar car 585.3 mi
    10h 42m
    $107–155

  3. Bus, train via Farragut

    1. Take the bus from Rehoboth P-N-R @ Country Club Rd to Wilmington Tcbus bus 305
    2. Take the train from Wilmington to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    19h 47m
    $216–913

  4. Bus, train

    1. Take the bus from Rehoboth P-N-R @ Country Club Rd to Wilmington Tcbus bus 305
    2. Take the train from Wilmington to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    19h 51m
    $171–823

  5. Bus

    1. Take the bus from Dewey Beach, DE to Penn Station NYbus bus Dewey Beach
    2. Take the bus from New York to Knoxvillebus bus Nyc
    20h 54m
    $224–321

Salisbury–Ocean City–Wicomico Regional Airport (SBY) to Mcghee Tyson Airport (TYS) flights

Calendar29Weekly Planes
Duration4h 36mAverage Duration
Ticket$121Cheapest Price
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Questions & Answers

Map of how to get from Millsboro to Knoxville.ExpandLaunch map view
  • Distance: 536.4 mi
  • Duration: 4h 58m

What companies run services between Millsboro, DE, USA and Knoxville, TN, USA?

You can take a bus from Railroad St @ Central Alley to Knoxville via Rehoboth P-N-R @ Country Club Rd, Dewey Beach, DE, Penn Station NY, W 34 St/10 Av, W 34 St/Broadway, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 20h 54m.

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