What is the cheapest way to get from Millsboro to Lancaster?

The cheapest way to get from Millsboro to Lancaster is to drive which costs $23 - $35 and takes 2h 54m.

What is the fastest way to get from Millsboro to Lancaster?

The fastest way to get from Millsboro to Lancaster is to drive which takes 2h 54m and costs $23 - $35.

Is there a direct bus between Millsboro and Lancaster?

No, there is no direct bus from Millsboro to Lancaster. However, there are services departing from Railroad St @ Central Alley and arriving at W. Chestnut & Water St. via Rehoboth P-N-R @ Country Club Rd, Wilmington Bus Station, Philadelphia Bus Station and AMTRAK ETown. The journey, including transfers, takes approximately 11h 57m.

How far is it from Millsboro to Lancaster?

The distance between Millsboro and Lancaster is 245 miles. The road distance is 128.9 miles.

How do I travel from Millsboro to Lancaster without a car?

The best way to get from Millsboro to Lancaster without a car is to bus and train which takes 9h 9m and costs $35 - $650.

How long does it take to get from Millsboro to Lancaster?

It takes approximately 9h 9m to get from Millsboro to Lancaster, including transfers.

Where do I catch the Millsboro to Lancaster bus from?

Millsboro to Lancaster bus services, operated by DART First State, depart from Rehoboth P-N-R @ Country Club Rd station.

Where does the Millsboro to Lancaster bus arrive?

Millsboro to Lancaster bus services, operated by DART First State, arrive at Wilmington Tc station.

Can I drive from Millsboro to Lancaster?

Yes, the driving distance between Millsboro to Lancaster is 129 miles. It takes approximately 2h 54m to drive from Millsboro to Lancaster.

Where can I stay near Lancaster?

There are 249+ hotels available in Lancaster.

Millsboro to Lancaster - 3 ways to travel via train, bus, and car

How to get fromMillsboro to Lancaster

Travel from

See all options

Search accommodation with Expedia

There are 3 ways to get from Millsboro to Lancaster by bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus, train
best
1. Take the bus from Rehoboth P-N-R @ Country Club Rd to Wilmington Tcbus 305
2. Take the train from Wilmington to 30th Street Stationtrain
3. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain
9h 9m
$39–620
Drive 128.2 mi
cheapest
1. Drive from Millsboro to Lancastercar 128.2 mi
2h 54m
$24–34
Bus
1. Take the bus from Rehoboth P-N-R @ Country Club Rd to Wilmington Tcbus 305
2. Take the bus from Wilmington Bus Station to Philadelphia Bus Stationbus
3. Take the bus from Philadelphia Bus Station to Harrisburg Bus Stationbus
11h 57m
$32–61

Millsboro to Lancaster by bus and train

12Weekly Services

9h 9mAverage Duration

$39Cheapest Price

See schedules

Questions & Answers

Map of how to get from Millsboro to Lancaster.

Launch map view

Distance: 243.4 mi
Duration: 9h 9m

What companies run services between Millsboro, DE, USA and Lancaster, PA, USA?

You can take a bus from Railroad St @ Central Alley to W. Chestnut & Water St. via Rehoboth P-N-R @ Country Club Rd, Wilmington Tc, Wilmington Bus Station, Philadelphia Bus Station, Harrisburg Bus Station, Harrisburg, Elizabethtown Amtrak Station, and AMTRAK ETown in around 11h 57m.

Train operators

Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.