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How to get fromMilwaukee Airport (MKE) to Buffaloby plane, bus, bus (Flixbus), train (Amtrak), bus (Flixbus, Greyhound), or car

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There are 6 ways to get from Milwaukee Airport (MKE) to Buffalo by plane, bus, bus (Flixbus), train (Amtrak), bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from General Mitchell International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Buffalo Niagara International Airport (BUF)plane plane MKE - BUF
    4h 3m
    $130–744

  2. Bus

    cheapest
    1. Take the bus from Milwaukee Mitchell Airport to Chicago Bus Stationbus bus
    2. Take the bus from Chicago to Clevelandbus bus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    14h
    $61–162

  3. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Mitchell Airport to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane plane ORD - BUF
    5h 2m
    $208–367

  4. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train Hiawatha Service / ...
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    15h 41m
    $191–564

  5. Bus via Detroit

    1. Take the bus from Milwaukee Mitchell Airport to Detroit Bus Stationbus bus
    2. Take the bus from Detroit Bus Station to Torontobus bus
    3. Take the bus from Toronto to Buffalobus bus
    18h 28m
    $108–190

  6. Drive 614.7 mi

    1. Drive from Milwaukee Airport (MKE) to Buffalocar car 614.7 mi
    10h 36m
    $113–163

Milwaukee Airport (MKE) to Buffalo by bus

Calendar7Weekly Buses
Duration14hAverage Duration
Ticket$61Cheapest Price
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Questions & Answers

Map of how to get from Milwaukee Airport (MKE) to Buffalo.ExpandLaunch map view
  • Distance: 477.7 mi
  • Duration: 4h 3m

What companies run services between Milwaukee Airport (MKE), USA and Buffalo, NY, USA?

Southwest Airlines, Delta, and two other airlines fly from General Mitchell International Airport (MKE) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Milwaukee Mitchell Airport to Buffalo, NY via Chicago and Cleveland, OH in around 14h.

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