There are 6 ways to get from Milwaukee Airport (MKE) to La Crosse by plane, bus, train (Amtrak), rideshare, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from General Mitchell International Airport
best- Fly from General Mitchell International Airport (MKE) to La Crosse (LSE)plane MKE - LSE
3h 40m$84–445Drive 215.4 mi
cheapest- Drive from Milwaukee Airport (MKE) to La Crossecar 215.4 mi
3h 40m$40–57Bus to Chicago O'Hare International Airport, fly
- Take the bus from Mitchell Airport to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to La Crosse (LSE)plane ORD - LSE
4h 5m$95–341Train (Amtrak)
- Take the train from Milwaukee to La Crosse Amtrak Stationtrain Empire Builder / ...
4h 47m$62–144Bus
- Take the bus from Milwaukee to La Crossebus Jefferson Lines 966
5h 8m$52–89Airport Transfer
- Take the rideshare from Milwaukee-MKE to La Crosse215.4 mi
3h 40m
Milwaukee Airport (MKE) to La Crosse by bus and train (Amtrak)
Questions & Answers
The cheapest way to get from Milwaukee Airport (MKE) to La Crosse is to drive which costs $35 - $60 and takes 3h 40m.
The fastest way to get from Milwaukee Airport (MKE) to La Crosse is to drive which takes 3h 40m and costs $35 - $60.
No, there is no direct bus from Milwaukee Airport (MKE) to La Crosse. However, there are services departing from Airport Departure and arriving at La Crosse via Milwaukee. The journey, including transfers, takes approximately 5h 8m.
No, there is no direct train from Milwaukee Airport (MKE) to La Crosse station. However, there are services departing from Milwaukee and arriving at La Crosse Amtrak Station via . The journey, including transfers, takes approximately 4h 47m.
The distance between Milwaukee Airport (MKE) and La Crosse is 189 miles. The road distance is 216.6 miles.
The best way to get from Milwaukee Airport (MKE) to La Crosse without a car is to train which takes 4h 47m and costs $60 - $150.
It takes approximately 3h 40m to get from Milwaukee Airport (MKE) to La Crosse, including transfers.
Milwaukee Airport (MKE) to La Crosse bus services, operated by Jefferson Lines, depart from Milwaukee station.
Milwaukee Airport (MKE) to La Crosse train services, operated by Amtrak, depart from Milwaukee station.
The best way to get from Milwaukee Airport (MKE) to La Crosse is to fly which takes 3h 40m and costs $80 - $450. Alternatively, you can train, which costs $60 - $150 and takes 4h 47m, you could also bus, which costs $50 - $90 and takes 5h 8m.
What companies run services between Milwaukee Airport (MKE), USA and La Crosse, WI, USA?
United Airlines and American Airlines fly from General Mitchell International Airport (MKE) to La Crosse (LSE) every 4 hours. Alternatively, Amtrak operates a train from Milwaukee to La Crosse Amtrak Station 3 times a day. Tickets cost $60–130 and the journey takes 3h 19m.
- Website
- aa.com
Flights from General Mitchell International Airport to La Crosse via Chicago O'Hare International Airport
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $65–430
Flights from Chicago O'Hare International Airport to La Crosse
- Ave. Duration
- 1h 21m
- When
- Every day
- Estimated price
- $40–280
- Website
- united.com
Flights from General Mitchell International Airport to La Crosse via Chicago O'Hare International Airport
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $65–430
Flights from Chicago O'Hare International Airport to La Crosse
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $40–280
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to La Crosse Amtrak Station
- Ave. Duration
- 3h 19m
- Frequency
- 3 times a day
- Estimated price
- $60–130
- Website
- Amtrak
- Phone
- (866) 912 6224
- [email protected]
- Website
- coachusa.com
Bus from Mitchell Airport to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- $35–39
- Website
- coachusa.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee to La Crosse
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
- Website
- https://www.mozio.com
Rideshare from Milwaukee-MKE to La Crosse
- Ave. Duration
- 3h 40m
- Frequency
- On demand
Want to know more about travelling around United States
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More Questions & Answers
Milwaukee Airport (MKE) to La Crosse bus services, operated by Jefferson Lines, arrive at La Crosse station.
Milwaukee Airport (MKE) to La Crosse train services, operated by Amtrak, arrive at La Crosse Amtrak Station.
Yes, the driving distance between Milwaukee Airport (MKE) to La Crosse is 217 miles. It takes approximately 3h 40m to drive from Milwaukee Airport (MKE) to La Crosse.
There are 46+ hotels available in La Crosse.
Check out Blablacar's carpooling service for rideshare options between Milwaukee Airport (MKE) and La Crosse. A great option if you don't have a driver's licence or want to avoid public transport.







