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How to get fromMilwaukee Airport (MKE) to Louisvilleby plane, bus, bus (Greyhound, Amtrak), train, bus (Flixbus, Amtrak), rideshare, or car

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There are 7 ways to get from Milwaukee Airport (MKE) to Louisville by plane, bus, bus (Greyhound, Amtrak), train, bus (Flixbus, Amtrak), rideshare, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from General Mitchell International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Louisville International Airport (SDF)plane plane MKE - SDF
    4h 6m
    $108–664

  2. Bus

    cheapest
    1. Take the bus from Milwaukee Mitchell Airport to Chicago Bus Stationbus bus FlixBus 2548 / ...
    2. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    10h 4m
    $63–81

  3. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Mitchell Airport to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    5h 11m
    $102–471

  4. Bus via Indianapolis

    1. Take the bus from Mitchell Airport to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    10h
    $86–143

  5. Train, bus (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    12h 16m
    $110–244

  6. Airport Transfer

    1. Take the rideshare from Milwaukee-MKE to Louisvillerideshare rideshare 376.9 mi
    6h 36m

  7. Drive 376.9 mi

    1. Drive from Milwaukee Airport (MKE) to Louisvillecar car 376.9 mi
    6h 36m
    $69–100

Milwaukee Airport (MKE) to Louisville by bus, subway, and foot

Calendar14Weekly Services
Duration10hAverage Duration
Ticket$86Cheapest Price
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Questions & Answers

Map of how to get from Milwaukee Airport (MKE) to Louisville.ExpandLaunch map view
  • Distance: 354.1 mi
  • Duration: 4h 6m

What companies run services between Milwaukee Airport (MKE), USA and Louisville, KY, USA?

Southwest Airlines, Delta, and two other airlines fly from General Mitchell International Airport (MKE) to Louisville International Airport (SDF) hourly. Alternatively, you can take a bus from Mitchell Airport to Louisville, KY via O'Hare International Airport - Terminal 2 Departures, O'Hare, LaSalle, Chicago Bus Station, and Indianapolis Union Station in around 10h.

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