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How to get fromMilwaukee to Ankenyby bus (Greyhound, Flixbus), car, plane, train, bus, or bus (Greyhound)

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There are 8 ways to get from Milwaukee to Ankeny by bus (Greyhound, Flixbus), car, plane, train, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus Greyhound US0150
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    9h 17m
    $77–143

  2. Drive 351 mi

    cheapest
    1. Drive from Milwaukee to Ankenycar car 351 mi
    6h 18m
    $65–93

  3. Fly from General Mitchell International Airport

    1. Fly from General Mitchell International Airport (MKE) to Des Moines (DSM)plane plane MKE - DSM
    6h 3m
    $162–942

  4. Train, bus

    1. Take the train from Milwaukee to Chicago Union Stationtrain train Hiawatha Service / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    9h 20m
    $90–172

  5. Bus via Chicago O'Hare Airport (ORD)

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus Wisconsin Coach Lines
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    10h 33m
    $104–164

  6. Train, bus via Galesburg

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    3. Take the bus from Galesburg to Des Moinesbus bus
    11h 12m
    $120–247

  7. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane plane ORD - DSM
    5h 16m
    $153–721

  8. Train to Chicago Midway International Airport, fly

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)plane plane MDW - DSM
    5h 41m
    $161–852

General Mitchell International Airport (MKE) to Des Moines (DSM) flights

Calendar134Weekly Planes
Duration4h 56mAverage Duration
Ticket$121Cheapest Price
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Questions & Answers

Map of how to get from Milwaukee to Ankeny.ExpandLaunch map view
  • Distance: 430.1 mi
  • Duration: 9h 17m

What companies run services between Milwaukee, WI, USA and Ankeny, IA, USA?

You can take a bus from Milwaukee Intermodal Station to Ankeny via Chicago Bus Station and Des Moines in around 9h 17m. Alternatively, Delta, Southwest Airlines, and two other airlines fly from General Mitchell International Airport (MKE) to Des Moines (DSM) hourly.

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Bus operators

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