There are 7 ways to get from Milwaukee to Biloxi by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly General Mitchell International Airport to Gulfport-Biloxi Regional Airport
best- Fly from General Mitchell International Airport (MKE) to Gulfport-Biloxi Regional Airport (GPT)plane MKE - GPT
6h 57m$157–697Bus to Chicago O'Hare International Airport, fly to Gulfport-Biloxi Regional Airport
cheapest- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Gulfport-Biloxi Regional Airport (GPT)plane ORD - GPT
8h 21m$143–456Train (Amtrak)
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain
24h 34m$587–942Bus via LaGrange
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to La Grange Bus Stationbus
- Take the bus from La Grange Bus Station to Biloxibus
26h 43m$210–340Drive 987.6 mi
- Drive from Milwaukee to Biloxicar 987.6 mi
16h 28m$181–261Fly General Mitchell International Airport to Mobile Regional Airport, bus
- Fly from General Mitchell International Airport (MKE) to Mobile Regional Airport (MOB)plane MKE - MOB
- Take the bus from Mobile Bus Station to Biloxi Transit Centerbus
8h 35m$155–647Bus
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Take the bus from Chicago Train Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Biloxi Transit Centerbus
29h 52m$248–369
Milwaukee to Biloxi by train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Milwaukee to Biloxi is to drive which costs $180 - $260 and takes 16h 28m.
The fastest way to get from Milwaukee to Biloxi is to fly which takes 6h 57m and costs $150 - $700.
No, there is no direct bus from Milwaukee station to Biloxi. However, there are services departing from Milwaukee Intermodal Station and arriving at Biloxi via Chicago Bus Station, Atlanta Bus Station and La Grange Bus Station. The journey, including transfers, takes approximately 26h 43m.
No, there is no direct train from Milwaukee to Biloxi. However, there are services departing from Milwaukee and arriving at Biloxi Amtrak Sta via Chicago Union Station and New Orleans Union Passenger Terminal. The journey, including transfers, takes approximately 24h 34m.
The distance between Milwaukee and Biloxi is 895 miles. The road distance is 993.3 miles.
The best way to get from Milwaukee to Biloxi without a car is to train which takes 24h 34m and costs $550 - $950.
It takes approximately 6h 57m to get from Milwaukee to Biloxi, including transfers.
Milwaukee to Biloxi bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
Milwaukee to Biloxi train services, operated by Amtrak, depart from Milwaukee station.
The best way to get from Milwaukee to Biloxi is to fly which takes 6h 57m and costs $150 - $700. Alternatively, you can train, which costs $550 - $950 and takes 24h 34m, you could also bus via LaGrange, which costs $210 - $340 and takes 26h 43m.
What companies run services between Milwaukee, WI, USA and Biloxi, MS, USA?
American Airlines, Delta, and United Airlines fly from General Mitchell International Airport (MKE) to Gulfport-Biloxi Regional Airport (GPT) 5 times a day. Alternatively, you can take a train from Milwaukee to Biloxi Amtrak Sta via Chicago Union Station and New Orleans Union Passenger Terminal in around 24h 34m.
- Website
- aa.com
Flights from General Mitchell International Airport to Gulfport-Biloxi Regional Airport via Charlotte
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $140–700
Flights from General Mitchell International Airport to Gulfport-Biloxi Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $150–700
Flights from Chicago O'Hare International Airport to Gulfport-Biloxi Regional Airport via Charlotte
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $80–400
Flights from Chicago O'Hare International Airport to Gulfport-Biloxi Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $90–420
Flights from General Mitchell International Airport to Mobile Regional Airport via Charlotte
- Ave. Duration
- 5h 22m
- When
- Thursday to Saturday
- Estimated price
- $130–650
Flights from General Mitchell International Airport to Mobile Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $150–750
- Website
- delta.com
Flights from General Mitchell International Airport to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 6h 32m
- When
- Every day
- Estimated price
- $120–650
Flights from Chicago O'Hare International Airport to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $70–370
Flights from General Mitchell International Airport to Mobile Regional Airport via Atlanta
- Ave. Duration
- 5h 23m
- When
- Every day
- Estimated price
- $120–600
Flights from General Mitchell International Airport to Mobile Regional Airport via Detroit, Atlanta
- Ave. Duration
- 8h 34m
- When
- Every day
- Estimated price
- $130–650
- Website
- united.com
Flights from General Mitchell International Airport to Gulfport-Biloxi Regional Airport via Houston
- Ave. Duration
- 8h 8m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–700
Flights from Chicago O'Hare International Airport to Gulfport-Biloxi Regional Airport via Houston
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- $90–420
Flights from General Mitchell International Airport to Mobile Regional Airport via Houston
- Ave. Duration
- 8h 7m
- When
- Saturday
- Estimated price
- $150–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Chicago Union Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 19h 42m
- Frequency
- Once daily
- Estimated price
- $500–800
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Biloxi Amtrak Sta
- Ave. Duration
- 1h 23m
- Frequency
- Twice daily
- Estimated price
- $40–70
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- $16–24
- Website
- Greyhound
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 5m
- Frequency
- 4 times a day
- Estimated price
- $130–200
- Website
- Greyhound
Bus from Atlanta Bus Station to La Grange Bus Station
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $11–17
- Website
- Greyhound
Bus from Mobile Bus Station to Biloxi Transit Center
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $10–15
- Website
- Greyhound
Bus from Chicago Train Station to Atlanta Bus Station
- Ave. Duration
- 15h 55m
- Frequency
- Twice daily
- Estimated price
- $130–200
- Website
- Greyhound
Bus from Atlanta Bus Station to Biloxi Transit Center
- Ave. Duration
- 8h 55m
- Frequency
- Twice daily
- Estimated price
- $75–120
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $14–21
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h
- Frequency
- 3 times a day
- Estimated price
- $110–170
- Schedules at
- Flixbus USA
Bus from Mobile Bus Station to Biloxi Transit Center
- Ave. Duration
- 55 min
- Frequency
- 6 times a week
- Estimated price
- $8–13
- Schedules at
- Flixbus USA
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from La Grange Bus Station to Biloxi
- Ave. Duration
- 4h 58m
- Frequency
- Once daily
- Estimated price
- $75–100
- Schedules at
- Omnibus Express
- Phone
- (866) 912 6224
- [email protected]
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
Want to know more about travelling around United States
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Booking & Getting There
Milwaukee to Biloxi bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Milwaukee to Biloxi train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Milwaukee to Biloxi is 993 miles. It takes approximately 16h 28m to drive from Milwaukee to Biloxi.
Book your Milwaukee to Biloxi train tickets online with Omio.
Book your Milwaukee to Biloxi bus tickets online with Omio.
There are 386+ hotels available in Biloxi.









