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How to get fromMilwaukee to Cairoby train, taxi, bus, car, or plane

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There are 9 ways to get from Milwaukee to Cairo by train, taxi, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, taxi

    best
    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carbondaletrain train
    3. Take the taxi from Carbondale to Cairotaxi taxi
    9h
    $248–415

  2. Drive 459.2 mi

    cheapest
    1. Drive from Milwaukee to Cairocar car 459.2 mi
    7h 41m
    $84–121

  3. Bus, taxi

    1. Take the bus from Water & Chicago - Circle K to Flying J - Matthewsbus bus Milwaukee
    2. Take the taxi from Flying J - Matthews to Cairotaxi taxi
    9h 41m
    $186–323

  4. Fly General Mitchell International Airport to Barkley Regional Airport, taxi

    1. Fly from General Mitchell International Airport (MKE) to Barkley Regional Airport (PAH)plane plane MKE - PAH
    2. Take the taxi from Barkley Regional Airport (PAH) to Cairotaxi taxi
    6h 47m
    $142–550

  5. Bus, taxi via Chicago

    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Paducah Bus Stationbus bus
    3. Take the taxi from Paducah Bus Station to Cairotaxi taxi
    14h 5m
    $209–297

  6. Bus to Chicago O'Hare International Airport, fly to Williamson County Regional Airport, taxi

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane plane ORD - MWA
    3. Take the taxi from Williamson County Regional Airport (MWA) to Cairotaxi taxi
    5h 14m
    $235–421

  7. Bus to Chicago O'Hare International Airport, fly to Barkley Regional Airport, taxi

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane plane ORD - PAH
    3. Take the taxi from Barkley Regional Airport (PAH) to Cairotaxi taxi
    4h 59m
    $145–421

  8. Bus to Chicago O'Hare International Airport, fly to Cape Girardeau Municipal Airport, taxi

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    3. Take the taxi from Cape Girardeau Municipal Airport (CGI) to Cairotaxi taxi
    5h 28m
    $215–361

  9. Fly General Mitchell International Airport to Lambert–St. Louis International Airport, bus, taxi

    1. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Cairotaxi taxi
    7h 23m
    $600–1,018

General Mitchell International Airport (MKE) to Barkley Regional Airport (PAH) flights

Calendar21Weekly Planes
Duration5h 59mAverage Duration
Ticket$78Cheapest Price
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Questions & Answers

Map of how to get from Milwaukee to Cairo.ExpandLaunch map view
  • Distance: 446.6 mi
  • Duration: 9h

What companies run services between Milwaukee, WI, USA and Cairo, IL, USA?

There is no direct connection from Milwaukee to Cairo. However, you can take the train to Chicago Union Station, take the train to Carbondale, then take the taxi to Cairo. Alternatively, you can take the bus to Flying J - Matthews then take the taxi to Cairo.

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