There are 11 ways to get from Milwaukee to Cape Girardeau by bus, plane, train, taxi, car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Chicago O'Hare International Airport, fly to Cape Girardeau Municipal Airport
best- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane ORD - CGI
4h 37m$161–459Drive 459.1 mi
cheapest- Drive from Milwaukee to Cape Girardeaucar 459.1 mi
7h 51m$84–121Train, taxi
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Carbondaletrain
- Take the taxi from Carbondale to Cape Girardeautaxi
8h 59m$317–472Bus, taxi
- Take the bus from Water & Chicago - Circle K to Marathon Gas Station - Marionbus Milwaukee
- Take the taxi from Anna - Shell to Cape Girardeautaxi
9h 38m$161–217Bus to Chicago O'Hare International Airport, fly to Williamson County Regional Airport, taxi
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane ORD - MWA
- Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi
5h 33m$248–411Fly General Mitchell International Airport to Lambert–St. Louis International Airport, bus
- Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane MKE - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
6h 32m$512–894Bus to Chicago O'Hare International Airport, fly to Barkley Regional Airport, taxi
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane ORD - PAH
- Take the taxi from Barkley Regional Airport (PAH) to Cape Girardeautaxi
5h 49m$218–491Bus to Chicago O'Hare International Airport, fly to Lambert–St. Louis International Airport, bus
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane ORD - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
8h 1m$338–783Fly General Mitchell International Airport to Cape Girardeau Municipal Airport
- Fly from General Mitchell International Airport (MKE) to Cape Girardeau Municipal Airport (CGI)plane MKE - CGI
5h 42m$205–730Train, bus
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Louistrain
- Take the bus from St Louis Bus Station to Cape Girardeaubus
10h 24m$224–351Bus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Cape Girardeaubus
11h 39m$86–137
Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI) flights
Comparing Your Travel Options
The cheapest way to get from Milwaukee to Cape Girardeau is to drive which costs $80 - $130 and takes 7h 51m.
The fastest way to get from Milwaukee to Cape Girardeau is to bus and fly which takes 4h 37m and costs $160 - $460.
No, there is no direct bus from Milwaukee station to Cape Girardeau. However, there are services departing from Milwaukee Intermodal Station and arriving at Cape Girardeau via Chicago Bus Station and St Louis Bus Station. The journey, including transfers, takes approximately 11h 39m.
The distance between Milwaukee and Cape Girardeau is 432 miles. The road distance is 461.7 miles.
The best way to get from Milwaukee to Cape Girardeau without a car is to train and taxi which takes 8h 59m and costs $310 - $480.
It takes approximately 4h 37m to get from Milwaukee to Cape Girardeau, including transfers.
Milwaukee to Cape Girardeau bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
The best way to get from Milwaukee to Cape Girardeau is to fly which takes 5h 42m and costs $200 - $750. Alternatively, you can bus, which costs $85 - $140 and takes 11h 39m.
Milwaukee to Cape Girardeau bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Yes, the driving distance between Milwaukee to Cape Girardeau is 462 miles. It takes approximately 7h 51m to drive from Milwaukee to Cape Girardeau.
What companies run services between Milwaukee, WI, USA and Cape Girardeau, MO, USA?
American Airlines, Corporate Flight Management Inc, and United Airlines fly from General Mitchell International Airport (MKE) to Cape Girardeau Municipal Airport (CGI) 3 times a day. Alternatively, you can take a bus from Milwaukee Intermodal Station to Cape Girardeau via Chicago Bus Station, St Louis Bus Station, and Cape Girardeau in around 11h 39m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Barkley Regional Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $40–280
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $50–340
- Website
- southwest.com
Flights from General Mitchell International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $85–600
Flights from General Mitchell International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 3h 13m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $85–600
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Williamson County Regional Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $40–280
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $50–340
- Website
- contouraviation.com
Flights from Chicago O'Hare International Airport to Cape Girardeau Municipal Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $100–390
Flights from General Mitchell International Airport to Cape Girardeau Municipal Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $180–700
Flights from General Mitchell International Airport to Cape Girardeau Municipal Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 14m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–700
- Website
- gojetairlines.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $50–340
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Chicago Union Station to Carbondale
- Ave. Duration
- 5h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–270
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $150–240
- Website
- Amtrak
- Phone
- (866) 912 6224
- [email protected]
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Water & Chicago - Circle K to Marathon Gas Station - Marion
- Ave. Duration
- 7h 35m
- Frequency
- Once daily
- Estimated price
- $85–110
- Schedules at
- Tornado Bus Company
- Adult
- $85–110
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- $15–23
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $13–21
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- $45–75
- Schedules at
- Flixbus USA
- Ave. Duration
- 1h 6m
- Estimated price
- $70–170
Ace Taxi
- Phone
- +1 216-361-4700
- Website
- acetaxi.com
Ace Taxi
- Phone
- +1 216-361-4700
- Website
- acetaxi.com
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