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How to get fromMilwaukee to Carlisleby plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, train, or bus (Greyhound)

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There are 8 ways to get from Milwaukee to Carlisle by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly General Mitchell International Airport to Harrisburg International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Harrisburg International Airport (MDT)plane plane MKE - MDT
    7h 36m
    $99–556

  2. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train
    3. Take the train from Pittsburgh Amtrak Station to Harrisburgtrain train
    20h 9m
    $253–548

  3. Bus

    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus Greyhound US0150 / ...
    2. Take the bus from Chicago Bus Station to Harrisburg Bus Stationbus bus FlixBus N2640 / ...
    20h 21m
    $134–237

  4. Drive 731.4 mi

    1. Drive from Milwaukee to Carlislecar car 731.4 mi
    12h 12m
    $134–193

  5. Bus to Chicago O'Hare International Airport, fly to Harrisburg International Airport

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Harrisburg International Airport (MDT)plane plane ORD - MDT
    7h 20m
    $105–405

  6. Fly General Mitchell International Airport to Philadelphia International Airport, train

    1. Fly from General Mitchell International Airport (MKE) to Philadelphia International Airport (PHL)plane plane MKE - PHL
    2. Take the train from 30th Street Station to Harrisburgtrain train
    8h 47m
    $176–827

  7. Bus to Chicago O'Hare International Airport, fly to Penn State University Park Airport, bus

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Penn State University Park Airport (SCE)plane plane ORD - SCE
    3. Take the bus from State College Regional Airport to Harrisburg Bus Stationbus bus
    9h 19m
    $113–408

  8. Bus via Baltimore

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Take the bus from Chicago Bus Station to Baltimore Downtown Bus Stationbus bus
    3. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus
    26h 11m
    $162–290

Milwaukee to Carlisle by train, foot, and bus (Amtrak)

Calendar7Weekly Services
Duration20h 9mAverage Duration
Ticket$253Cheapest Price
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Questions & Answers

Map of how to get from Milwaukee to Carlisle.ExpandLaunch map view
  • Distance: 644.3 mi
  • Duration: 7h 36m

What companies run services between Milwaukee, WI, USA and Carlisle, PA, USA?

Delta, American Airlines, and United Airlines fly from General Mitchell International Airport (MKE) to Harrisburg International Airport (MDT) hourly. Alternatively, you can take a train from Milwaukee to N Hanover St & Louther St WB via Chicago Union Station, Pittsburgh Amtrak Station, Harrisburg, and Market Square Transfer Center in around 20h 9m.

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