There are 8 ways to get from Milwaukee to Charlotte by plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, train, or bus (Amtrak, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from General Mitchell International Airport
best- Fly from General Mitchell International Airport (MKE) to Charlotte Douglas International Airport (CLT)plane MKE - CLT
4h 10m$135–755Bus via Columbus
- Take the bus from Milwaukee Intermodal Station to Columbusbus FlixBus 2511
- Take the bus from Columbus - Mound St to Charlotte Bus Stationbus Columbus / ...
21h 3m$139–223Train (Amtrak)
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Carytrain
- Take the train from Cary to Charlotte Amtrak Stationtrain
30h 53m$321–799Drive 817.4 mi
- Drive from Milwaukee to Charlottecar 817.4 mi
15h 8m$150–216Bus to Chicago O'Hare International Airport, fly
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Charlotte Douglas International Airport (CLT)plane ORD - CLT
5h 32m$161–434Bus to Dane County Regional Airport-Truax Field, fly
- Take the bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.bus
- Fly from Dane County Regional Airport-Truax Field (MSN) to Charlotte Douglas International Airport (CLT)plane MSN - CLT
6h 20m$175–895Train to Chicago Midway International Airport, fly
- Take the train from Milwaukee to Chicago Union Stationtrain
- Fly from Chicago Midway International Airport (MDW) to Charlotte Douglas International Airport (CLT)plane MDW - CLT
5h 58m$136–757Bus
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Take the bus from Chicago Union Station to Toledobus
- Take the bus from Toledo Bus Stop to Charlotte Bus Stationbus
23h 35m$193–294
Milwaukee to Charlotte by bus
Comparing Your Travel Options
The cheapest way to get from Milwaukee to Charlotte is to bus via Columbus which costs $130 - $230 and takes 21h 3m.
The fastest way to get from Milwaukee to Charlotte is to fly which takes 4h 10m and costs $130 - $800.
No, there is no direct bus from Milwaukee station to Charlotte station. However, there are services departing from Milwaukee Intermodal Station and arriving at Charlotte Bus Station via E Main St & S High St and Columbus - Mound St. The journey, including transfers, takes approximately 21h 3m.
No, there is no direct train from Milwaukee to Charlotte station. However, there are services departing from Milwaukee and arriving at Charlotte Amtrak Station via Chicago Union Station and Cary. The journey, including transfers, takes approximately 30h 53m.
The distance between Milwaukee and Charlotte is 670 miles. The road distance is 822.2 miles.
The best way to get from Milwaukee to Charlotte without a car is to bus via Columbus which takes 21h 3m and costs $130 - $230.
It takes approximately 4h 10m to get from Milwaukee to Charlotte, including transfers.
Milwaukee to Charlotte bus services, operated by Flixbus USA, depart from Milwaukee Intermodal Station.
Milwaukee to Charlotte train services, operated by Amtrak, depart from Milwaukee station.
The best way to get from Milwaukee to Charlotte is to fly which takes 4h 10m and costs $130 - $800. Alternatively, you can bus via Columbus, which costs $130 - $230 and takes 21h 3m, you could also train, which costs $320 - $800 and takes 30h 53m.
What companies run services between Milwaukee, WI, USA and Charlotte, NC, USA?
American Airlines, Southwest Airlines, and two other airlines fly from General Mitchell International Airport (MKE) to Charlotte Douglas International Airport (CLT) hourly. Alternatively, you can take a bus from Milwaukee Intermodal Station to Charlotte Bus Station via Columbus, E Main St & S High St, S Grant Ave & E Mound St, and Columbus - Mound St in around 21h 3m.
- Website
- aa.com
Flights from General Mitchell International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 9m
- When
- Every day
- Estimated price
- $130–750
Flights from General Mitchell International Airport to Charlotte Douglas International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $130–800
Flights from Chicago O'Hare International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- $80–470
Flights from Chicago O'Hare International Airport to Charlotte Douglas International Airport via Covington
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $80–470
Flights from Chicago O'Hare International Airport to Charlotte Douglas International Airport via Asheville
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $85–480
Flights from Chicago O'Hare International Airport to Charlotte Douglas International Airport via Greensboro/High Point
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $85–490
Flights from Dane County Regional Airport-Truax Field to Charlotte Douglas International Airport
- Ave. Duration
- 2h 19m
- When
- Every day
- Estimated price
- $150–850
Flights from Dane County Regional Airport-Truax Field to Charlotte Douglas International Airport via Reagan Washington
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $200–1,000
Flights from Dane County Regional Airport-Truax Field to Charlotte Douglas International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $150–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $20–50
- Website
- Amtrak
Train from Chicago Union Station to Cary
- Ave. Duration
- 24h 26m
- Frequency
- Once daily
- Estimated price
- $260–650
- Website
- Amtrak
Train from Cary to Charlotte Amtrak Station
- Ave. Duration
- 2h 58m
- Frequency
- 5 times a day
- Estimated price
- $40–100
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $20–50
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Milwaukee Intermodal Station to Columbus
- Ave. Duration
- 9h 50m
- Frequency
- 6 times a week
- Estimated price
- $65–100
- Schedules at
- Flixbus USA
Bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $11–18
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
Milwaukee to Charlotte bus services, operated by Flixbus USA, arrive at Columbus station.
Charlotte is 1h ahead of Milwaukee. It is currently 10:55 PM in Milwaukee and 11:55 PM in Charlotte.
Milwaukee to Charlotte train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Milwaukee to Charlotte is 822 miles. It takes approximately 15h 8m to drive from Milwaukee to Charlotte.
Book your Milwaukee to Charlotte train tickets online with Omio.
Book your Milwaukee to Charlotte bus tickets online with Omio.
There are 941+ hotels available in Charlotte.





