There are 7 ways to get from Milwaukee to Cleveland Clinic by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, train, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from General Mitchell International Airport
best- Fly from General Mitchell International Airport (MKE) to Cleveland-Hopkins International Airport (CLE)plane MKE - CLE
5h 34m$105–605Bus
cheapest- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus Greyhound US0150 / ...
- Take the bus from Chicago to Clevelandbus Chicago
10h 24m$47–109Train (Amtrak)
- Take the train from Milwaukee to Chicago Union Stationtrain Hiawatha Service / ...
- Take the train from Chicago Union Station to Cleveland Amtraktrain Floridian / ...
9h 35m$141–289Drive 435.2 mi
- Drive from Milwaukee to Cleveland Cliniccar 435.2 mi
7h 28m$80–115Bus to Chicago O'Hare International Airport, fly
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Cleveland-Hopkins International Airport (CLE)plane ORD - CLE
5h 25m$411–844Train to Chicago Midway International Airport, fly
- Take the train from Milwaukee to Chicago Union Stationtrain
- Fly from Chicago Midway International Airport (MDW) to Cleveland-Hopkins International Airport (CLE)plane MDW - CLE
5h 41m$121–617Bus via Detroit
- Take the bus from Milwaukee Intermodal Station to Detroit Bus Stationbus FlixBus 2550
- Take the bus from Detroit Bus Station to Cleveland Bus Stationbus Greyhound US0420
12h 46m$87–150
Milwaukee to Cleveland Clinic by bus and foot
Questions & Answers
The cheapest way to get from Milwaukee to Cleveland Clinic is to bus which costs $45 - $110 and takes 10h 24m.
The fastest way to get from Milwaukee to Cleveland Clinic is to bus and fly which takes 5h 25m and costs $410 - $850.
No, there is no direct bus from Milwaukee station to Cleveland Clinic. However, there are services departing from Milwaukee Intermodal Station and arriving at E 105Th St & Carnegie Av via Chicago and Chester Av & E 15Th St. The journey, including transfers, takes approximately 10h 24m.
No, there is no direct train from Milwaukee to Cleveland Clinic station. However, there are services departing from Milwaukee and arriving at E 105Th St-Quincy Av Station via Chicago Union Station and Tower City Station Track 13. The journey, including transfers, takes approximately 9h 35m.
The distance between Milwaukee and Cleveland Clinic is 355 miles. The road distance is 437.7 miles.
The best way to get from Milwaukee to Cleveland Clinic without a car is to train which takes 9h 35m and costs $140 - $290.
It takes approximately 5h 34m to get from Milwaukee to Cleveland Clinic, including transfers.
Milwaukee to Cleveland Clinic bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
Milwaukee to Cleveland Clinic train services, operated by Amtrak, depart from Milwaukee station.
The best way to get from Milwaukee to Cleveland Clinic is to fly which takes 5h 34m and costs $100 - $650. Alternatively, you can train, which costs $140 - $290 and takes 9h 35m, you could also bus, which costs $45 - $110 and takes 10h 24m.
What companies run services between Milwaukee, WI, USA and Cleveland Clinic, OH, USA?
Delta, Southwest Airlines, and two other airlines fly from General Mitchell International Airport (MKE) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a train from Milwaukee to Cleveland Clinic via Chicago Union Station, Cleveland Amtrak, Tower City Station Track 13, and E 105Th St-Quincy Av Station in around 9h 35m.
- Website
- southwest.com
Flights from General Mitchell International Airport to Cleveland-Hopkins International Airport via Chicago Midway International Airport
- Ave. Duration
- 3h 10m
- When
- Saturday and Sunday
- Estimated price
- $100–650
Flights from General Mitchell International Airport to Cleveland-Hopkins International Airport via St. Louis
- Ave. Duration
- 4h 6m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $160–800
Flights from General Mitchell International Airport to Cleveland-Hopkins International Airport via Nashville
- Ave. Duration
- 4h
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $180–850
Flights from General Mitchell International Airport to Cleveland-Hopkins International Airport via Baltimore
- Ave. Duration
- 4h 30m
- When
- Sunday, Tuesday, Wednesday, and Saturday
- Estimated price
- $180–900
Flights from Chicago Midway International Airport to Cleveland-Hopkins International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $85–550
- Website
- united.com
Flights from General Mitchell International Airport to Cleveland-Hopkins International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $100–650
Flights from Chicago O'Hare International Airport to Cleveland-Hopkins International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $65–420
- Website
- aa.com
Flights from General Mitchell International Airport to Cleveland-Hopkins International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $100–650
Flights from Chicago O'Hare International Airport to Cleveland-Hopkins International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $65–420
- Website
- delta.com
Flights from General Mitchell International Airport to Cleveland-Hopkins International Airport via Detroit
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- $100–600
Flights from Chicago O'Hare International Airport to Cleveland-Hopkins International Airport via Detroit
- Ave. Duration
- 3h 41m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $65–420
Flights from Chicago Midway International Airport to Cleveland-Hopkins International Airport via Detroit
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- $85–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $27–60
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Cleveland Amtrak
- Ave. Duration
- 6h 5m
- Frequency
- 3 times a day
- Estimated price
- $110–230
- Website
- https://www.amtrak.com/home.html
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $27–60
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $14–27
- Website
- https://www.greyhound.com/
Bus from Detroit Bus Station to Cleveland Bus Station
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Estimated price
- $25–50
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $14–23
- Schedules at
- flixbus.com
Bus from Milwaukee Intermodal Station to Detroit Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- 4 times a week
- Estimated price
- $55–100
- Schedules at
- flixbus.com
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Chicago to Cleveland
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
- Phone
- (866) 912 6224
- [email protected]
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- https://www.coachusa.com/wisconsin-coach?gad_source=1&gclid=CjwKCAiAt4C-BhBcEiwA8Kp0Cc3RRg_kOdc3CzsoiFSe4BX-r10-kIOeuDNMfsAKsG5uubvoAmxcrRoC5LwQAvD_BwE
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More Questions & Answers
Milwaukee to Cleveland Clinic bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Milwaukee to Cleveland Clinic train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Milwaukee to Cleveland Clinic is 438 miles. It takes approximately 7h 28m to drive from Milwaukee to Cleveland Clinic.
There are 632+ hotels available in Cleveland Clinic.











