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How to get fromMilwaukee to Columbiaby plane, train, taxi, bus (Greyhound, Flixbus), car, or bus

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There are 6 ways to get from Milwaukee to Columbia by plane, train, taxi, bus (Greyhound, Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from General Mitchell International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Columbia Regional Airport (COU)plane plane MKE - COU
    5h 34m
    $127–517

  2. Bus

    cheapest
    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Columbiabus bus
    12h 30m
    $84–155

  3. Train, taxi

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Jefferson City Stationtrain train
    3. Take the taxi from Jefferson City Station to Columbiataxi taxi
    10h 49m
    $267–476

  4. Drive 457.2 mi

    1. Drive from Milwaukee to Columbiacar car 457.2 mi
    8h 8m
    $84–121

  5. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane plane ORD - COU
    4h 34m
    $133–406

  6. Train, bus

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Columbiabus bus
    11h 15m
    $133–291

Milwaukee to Columbia by bus

Calendar28Weekly Buses
Duration12h 30mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

Map of how to get from Milwaukee to Columbia.ExpandLaunch map view
  • Distance: 384.2 mi
  • Duration: 5h 34m

What companies run services between Milwaukee, WI, USA and Columbia, MO, USA?

American Airlines and United Airlines fly from General Mitchell International Airport (MKE) to Columbia Regional Airport (COU) every 4 hours. Alternatively, you can take a bus from Milwaukee Intermodal Station to Columbia via Chicago Bus Station and St Louis Bus Station in around 12h 30m.

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