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How to get fromMilwaukee to East Saint Louisby plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or train

Find Transport to East Saint Louis

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There are 7 ways to get from Milwaukee to East Saint Louis by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from General Mitchell International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    3h 39m
    $485–865

  2. Bus

    cheapest
    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus Greyhound US0150 / ...
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    8h 51m
    $67–115

  3. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train Hiawatha Service / ...
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    7h 31m
    $121–248

  4. Drive 368.9 mi

    1. Drive from Milwaukee to East Saint Louiscar car 368.9 mi
    6h 13m
    $68–98

  5. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    5h
    $311–744

  6. Train to Chicago Midway International Airport, fly

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    5h 28m
    $116–616

  7. Bus, train

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus Wisconsin Coach Lines
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    8h 51m
    $133–239

Milwaukee to East Saint Louis by train (Amtrak)

Calendar38Weekly Trains
Duration7h 31mAverage Duration
Ticket$121Cheapest Price
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Questions & Answers

Map of how to get from Milwaukee to East Saint Louis.ExpandLaunch map view
  • Distance: 343.6 mi
  • Duration: 3h 39m

What companies run services between Milwaukee, WI, USA and East Saint Louis, IL, USA?

Southwest Airlines flies from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL) twice daily. Alternatively, you can take a train from Milwaukee to 5TH & MISSOURI station via Chicago Union Station, St. Louis, and CIVIC CENTER station in around 7h 31m.

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