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How to get fromMilwaukee to Florenceby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train

Find Transport to Florence

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There are 5 ways to get from Milwaukee to Florence by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from General Mitchell International Airport (MKE) to Florence Regional Airport (FLO)plane plane MKE - FLO
    7h 6m
    $122–575
  2. Bus

    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Florencebus bus
    23h 55m
    $169–336
  3. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Florence Stationtrain train
    29h 38m
    $403–835
  4. Drive 919.2 mi

    1. Drive from Milwaukee to Florencecar car 919.2 mi
    17h 28m
    $168–243
  5. Bus, train

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    32h 22m
    $406–798

Milwaukee to Florence by bus

Calendar49Weekly Buses
Duration23h 55mAverage Duration
Ticket$169Cheapest Price
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Questions & Answers

What companies run services between Milwaukee, WI, USA and Florence, SC, USA?

American Airlines flies from General Mitchell International Airport (MKE) to Florence Regional Airport (FLO) twice daily. Alternatively, you can take a bus from Milwaukee Intermodal Station to Florence via Chicago Bus Station and Atlanta in around 23h 55m.

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