There are 4 ways to get from Milwaukee to Florence by plane, bus (Greyhound, Flixbus), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from General Mitchell International Airport (MKE) to Florence Regional Airport (FLO)plane MKE - FLO
7h 38m$112–565Bus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Florence Bus Stationbus
26h$174–293Train (Amtrak)
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Raleigh Union Stationtrain
- Take the train from Raleigh Union Station to Selma Stationtrain
- Take the train from Selma Station to Florence Stationtrain
31h 43m$682–1,167Drive 919.2 mi
- Drive from Milwaukee to Florencecar 919.2 mi
17h 28m$168–243
Milwaukee to Florence by bus
Comparing Your Travel Options
The cheapest way to get from Milwaukee to Florence is to drive which costs $160 - $250 and takes 17h 28m.
The fastest way to get from Milwaukee to Florence is to fly which takes 7h 38m and costs $110 - $600.
No, there is no direct bus from Milwaukee station to Florence station. However, there are services departing from Milwaukee Intermodal Station and arriving at Florence Bus Station via Chicago Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 26h.
No, there is no direct train from Milwaukee to Florence station. However, there are services departing from Milwaukee and arriving at Florence Station via Chicago Union Station, Raleigh Union Station and Selma Station. The journey, including transfers, takes approximately 31h 43m.
The distance between Milwaukee and Florence is 762 miles. The road distance is 924.6 miles.
The best way to get from Milwaukee to Florence without a car is to bus which takes 26h and costs $170 - $300.
It takes approximately 7h 38m to get from Milwaukee to Florence, including transfers.
Milwaukee to Florence bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
Milwaukee to Florence train services, operated by Amtrak, depart from Milwaukee station.
The best way to get from Milwaukee to Florence is to fly which takes 7h 38m and costs $110 - $600. Alternatively, you can bus, which costs $170 - $300 and takes 26h, you could also train, which costs $650 - $1,200 and takes 31h 43m.
What companies run services between Milwaukee, WI, USA and Florence, SC, USA?
American Airlines flies from General Mitchell International Airport (MKE) to Florence Regional Airport (FLO) 4 times a day. Alternatively, you can take a bus from Milwaukee Intermodal Station to Florence Bus Station via Chicago Bus Station and Atlanta Bus Station in around 26h.
- Website
- aa.com
Flights from General Mitchell International Airport to Florence Regional Airport via Charlotte
- Ave. Duration
- 6h 54m
- When
- Every day
- Estimated price
- $100–550
Flights from General Mitchell International Airport to Florence Regional Airport via Chicago O'Hare, Charlotte
- Ave. Duration
- 8h 59m
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Chicago Union Station to Raleigh Union Station
- Ave. Duration
- 24h 1m
- Frequency
- Once daily
- Estimated price
- $550–950
- Website
- Amtrak
Train from Raleigh Union Station to Selma Station
- Ave. Duration
- 33 min
- Frequency
- Once daily
- Estimated price
- $15–25
- Website
- Amtrak
Train from Selma Station to Florence Station
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $70–120
- Website
- Amtrak
#mediaviewer/File:Super_Dome_car.jpg "Hiawatha dome car")
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- $15–23
- Website
- Greyhound
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 5m
- Frequency
- 4 times a day
- Estimated price
- $120–190
- Website
- Greyhound
Bus from Atlanta Bus Station to Florence Bus Station
- Ave. Duration
- 6h 20m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $13–21
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 15h 40m
- Frequency
- Twice daily
- Estimated price
- $110–170
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Milwaukee to Florence bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Florence is 1h ahead of Milwaukee. It is currently 9:37 PM in Milwaukee and 10:37 PM in Florence.
Milwaukee to Florence train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Milwaukee to Florence is 925 miles. It takes approximately 17h 28m to drive from Milwaukee to Florence.
Book your Milwaukee to Florence train tickets online with Omio.
Book your Milwaukee to Florence bus tickets online with Omio and FlixBus.
There are 32+ hotels available in Florence.