Rome2Rio

How to get fromMilwaukee to Greenvilleby plane, bus (Greyhound, Flixbus), train, bus, car, taxi, or bus (Flixbus)

Find Transport to Greenville

See all options

There are 7 ways to get from Milwaukee to Greenville by plane, bus (Greyhound, Flixbus), train, bus, car, taxi, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly General Mitchell International Airport to Greenville–Spartanburg International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Greenville–Spartanburg International Airport (GSP)plane plane MKE - GSP
    5h 13m
    $177–847

  2. Drive 756.3 mi

    cheapest
    1. Drive from Milwaukee to Greenvillecar car 756.3 mi
    14h 23m
    $138–200

  3. Bus

    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    24h 18m
    $179–410

  4. Train, bus

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    4. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    34h 57m
    $473–1,078

  5. Bus to Chicago O'Hare International Airport, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane plane ORD - GSP
    5h 7m
    $168–636

  6. Bus to Chicago O'Hare International Airport, fly to Asheville Regional Airport, taxi

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    3. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    5h 43m
    $238–551

  7. Bus via Bloomington

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Take the bus from Chicago Bus Station to Bloomingtonbus bus
    3. Take the bus from Bloomington to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    24h 56m
    $218–423

General Mitchell International Airport (MKE) to Greenville–Spartanburg International Airport (GSP) flights

Calendar123Weekly Planes
Duration5h 9mAverage Duration
Ticket$149Cheapest Price
See schedules

Questions & Answers

Map of how to get from Milwaukee to Greenville.ExpandLaunch map view
  • Distance: 654.3 mi
  • Duration: 5h 13m

What companies run services between Milwaukee, WI, USA and Greenville, SC, USA?

Southwest Airlines, Delta, and two other airlines fly from General Mitchell International Airport (MKE) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a bus from Milwaukee Intermodal Station to Greenville via Chicago Bus Station, Atlanta Bus Station, Garnett Station, Lindbergh Center Station, Lindbergh Center Station - Bay D, Shallowford Rd @ New Peachtree, Atlanta, and Taqueria Guadalajara - Greenville in around 24h 18m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers