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How to get fromMilwaukee to Jeffersonvilleby bus (Greyhound, Flixbus), train, bus, car, or plane

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There are 8 ways to get from Milwaukee to Jeffersonville by bus (Greyhound, Flixbus), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus FlixBus 2548 / ...
    2. Take the bus from Chicago Bus Station to Louisville Bus Stationbus bus Greyhound US0100 / ...
    10h 6m
    $62–124

  2. Train, bus via Speedway

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis to El Mercadito Grocery - Clarksville, INbus bus
    11h 47m
    $155–354

  3. Drive 381.2 mi

    1. Drive from Milwaukee to Jeffersonvillecar car 381.2 mi
    6h 42m
    $70–101

  4. Fly General Mitchell International Airport to Louisville International Airport

    1. Fly from General Mitchell International Airport (MKE) to Louisville International Airport (SDF)plane plane MKE - SDF
    6h 46m
    $104–676

  5. Train, bus

    1. Take the train from Milwaukee to Chicago Union Stationtrain train Hiawatha Service / ...
    2. Take the bus from Chicago Bus Station to Louisville Bus Stationbus bus Greyhound US0100 / ...
    10h 22m
    $75–151

  6. Bus to Chicago O'Hare International Airport, fly to Blue Grass Airport, drive

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    3. Drive from Lexington-Airport-LEX to Jeffersonvillecar car
    5h 41m
    $143–710

  7. Bus to Chicago O'Hare International Airport, fly to Louisville International Airport

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    6h 43m
    $97–457

  8. Train to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    6h 55m
    $115–619

Milwaukee to Jeffersonville by bus and foot

Calendar82Weekly Services
Duration10h 6mAverage Duration
Ticket$62Cheapest Price
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Questions & Answers

Map of how to get from Milwaukee to Jeffersonville.ExpandLaunch map view
  • Distance: 389.9 mi
  • Duration: 10h 6m

What companies run services between Milwaukee, WI, USA and Jeffersonville, IN, USA?

You can take a bus from Milwaukee Intermodal Station to Court @ Spring via Chicago Bus Station, Louisville Bus Station, Chestnut @ 13th, Chestnut @ 8th, and Liberty @ Roy Wilkins in around 10h 6m. Alternatively, Southwest Airlines, Delta, and two other airlines fly from General Mitchell International Airport (MKE) to Louisville International Airport (SDF) hourly.

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