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How to get fromMilwaukee to Kirksvilleby bus, plane, train (Amtrak), car, or train

Find Transport to Kirksville

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There are 5 ways to get from Milwaukee to Kirksville by bus, plane, train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Kirksville Regional Airport

    best
    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Kirksville Regional Airport (IRK)plane plane ORD - IRK
    4h 32m
    $152–390

  2. Drive  390.3 mi

    cheapest
    1. Drive from Milwaukee to Kirksvillecar car 390.3 mi
    7h 48m
    $72–103

  3. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train Hiawatha Service / ...
    2. Take the train from Chicago Union Station to La Plata Stationtrain train Southwest Chief
    7h 38m
    $242–382

  4. Bus, fly to Burlington Municipal Airport, drive

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Burlington Municipal Airport (BRL)plane plane ORD - BRL
    3. Drive from Burlington Municipal Airport (BRL) to Kirksvillecar car
    7h 4m
    $149–206

  5. Bus, train

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus Wisconsin Coach Lines
    2. Take the train from Chicago Union Station to La Plata Stationtrain train Southwest Chief
    9h 12m
    $238–359

Chicago O'Hare International Airport (ORD) to Kirksville Regional Airport (IRK) flights

Calendar7Weekly Planes
Duration1h 30mAverage Duration
Ticket$92Cheapest Price
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Comparing Your Travel Options

Map of how to get from Milwaukee to Kirksville.ExpandLaunch map view
  • Distance: 364.1 mi
  • Duration: 4h 32m

What companies run services between Milwaukee, WI, USA and Kirksville, MO, USA?

You can take a train from Milwaukee to Kirksville via Chicago Union Station and La Plata Station in around 7h 38m.

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