There are 5 ways to get from Milwaukee to La Crosse by train (Amtrak), bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Milwaukee to La Crosse Amtrak Stationtrain Empire Builder / ...
3h 19m$60–130Drive 209.9 mi
cheapest- Drive from Milwaukee to La Crossecar 209.9 mi
3h 31m$39–56Bus
- Take the bus from Milwaukee to La Crossebus Jefferson 966 / ...
3h 40m$55–80Fly from General Mitchell International Airport
- Fly from General Mitchell International Airport (MKE) to La Crosse (LSE)plane MKE - LSE
5h 8m$86–463Bus to Chicago O'Hare International Airport, fly
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to La Crosse (LSE)plane ORD - LSE
4h 25m$89–344
Milwaukee to La Crosse by train (Amtrak)
Questions & Answers
The cheapest way to get from Milwaukee to La Crosse is to drive which costs $35 - $60 and takes 3h 31m.
The fastest way to get from Milwaukee to La Crosse is to train which takes 3h 19m and costs $60 - $130.
Yes, there is a direct bus departing from Milwaukee and arriving at La Crosse. Services depart three times a day, and operate every day. The journey takes approximately 3h 40m.
Yes, there is a direct train departing from Milwaukee and arriving at La Crosse Amtrak Station station. Services depart three times a day, and operate every day. The journey takes approximately 3h 19m.
The distance between Milwaukee and La Crosse is 196 miles. The road distance is 211.1 miles.
The best way to get from Milwaukee to La Crosse without a car is to train which takes 3h 19m and costs $60 - $130.
The train from Milwaukee to La Crosse Amtrak Station takes 3h 19m including transfers and departs three times a day.
Milwaukee to La Crosse bus services, operated by Jefferson Lines, depart from Milwaukee station.
Milwaukee to La Crosse train services, operated by Amtrak, depart from Milwaukee station.
The best way to get from Milwaukee to La Crosse is to train which takes 3h 19m and costs $60 - $130. Alternatively, you can bus, which costs $55 - $80 and takes 3h 40m, you could also fly, which costs $85 - $470 and takes 5h 8m.
What companies run services between Milwaukee, WI, USA and La Crosse, WI, USA?
Amtrak operates a train from Milwaukee to La Crosse Amtrak Station 3 times a day. Tickets cost $60–130 and the journey takes 3h 19m. Alternatively, Jefferson Lines operates a bus from Milwaukee to La Crosse 3 times a day. Tickets cost $55–80 and the journey takes 3h 40m.
- Website
- aa.com
Flights from General Mitchell International Airport to La Crosse via Chicago O'Hare International Airport
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $65–420
Flights from Chicago O'Hare International Airport to La Crosse
- Ave. Duration
- 1h 21m
- When
- Every day
- Estimated price
- $40–280
- Website
- united.com
Flights from General Mitchell International Airport to La Crosse via Chicago O'Hare International Airport
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $65–420
Flights from Chicago O'Hare International Airport to La Crosse
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $40–280
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to La Crosse Amtrak Station
- Ave. Duration
- 3h 19m
- Frequency
- 3 times a day
- Estimated price
- $60–130
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee to La Crosse
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $55–80
- Book at
- https://www.jeffersonlines.com
- Adult
- $55–80
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Every 2 hours
- Estimated price
- $29–45
- Book at
- https://www.jeffersonlines.com
- Adult
- $29–45
- Phone
- (866) 912 6224
- [email protected]
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- https://www.coachusa.com/wisconsin-coach?gad_source=1&gclid=CjwKCAiAt4C-BhBcEiwA8Kp0Cc3RRg_kOdc3CzsoiFSe4BX-r10-kIOeuDNMfsAKsG5uubvoAmxcrRoC5LwQAvD_BwE
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More Questions & Answers
Milwaukee to La Crosse bus services, operated by Jefferson Lines, arrive at La Crosse station.
Milwaukee to La Crosse train services, operated by Amtrak, arrive at La Crosse Amtrak Station.
Yes, the driving distance between Milwaukee to La Crosse is 211 miles. It takes approximately 3h 31m to drive from Milwaukee to La Crosse.
Book your Milwaukee to La Crosse train tickets online with Omio.
Book your Milwaukee to La Crosse bus tickets online with Omio.
There are 45+ hotels available in La Crosse.