There are 9 ways to get from Milwaukee to Mechanicsburg by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, taxi, train, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly General Mitchell International Airport to Harrisburg International Airport
best- Fly from General Mitchell International Airport (MKE) to Harrisburg International Airport (MDT)plane MKE - MDT
7h 36m$94–556Train (Amtrak)
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain
- Take the train from Pittsburgh Amtrak Station to Harrisburgtrain
19h 23m$438–694Bus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus Greyhound US0150
- Take the bus from Chicago Bus Station to Harrisburg Bus Stationbus FlixBus N2640 / ...
19h 34m$135–205Drive 737.8 mi
- Drive from Milwaukee to Mechanicsburgcar 737.8 mi
12h 22m$135–195Bus to Chicago O'Hare International Airport, fly to Lancaster, taxi
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Lancaster (LNS)plane ORD - LNS
- Take the taxi from Lancaster-Airport-LNS to Mechanicsburgtaxi
5h 51m$233–541Bus to Chicago O'Hare International Airport, fly to Harrisburg International Airport
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Harrisburg International Airport (MDT)plane ORD - MDT
6h 32m$95–365Fly General Mitchell International Airport to Philadelphia International Airport, train
- Fly from General Mitchell International Airport (MKE) to Philadelphia International Airport (PHL)plane MKE - PHL
- Take the train from 30th Street Station to Harrisburgtrain
8h 4m$520–948Bus to Chicago O'Hare International Airport, fly to Penn State University Park Airport, bus
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Penn State University Park Airport (SCE)plane ORD - SCE
- Take the bus from State College Regional Airport to Harrisburg Bus Stationbus
8h 28m$103–375Bus via Baltimore
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Take the bus from Chicago Bus Station to Baltimore Downtown Bus Stationbus
- Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus
26h 9m$187–272
Milwaukee to Mechanicsburg by train, foot, and bus (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Milwaukee to Mechanicsburg is to bus which costs $130 - $210 and takes 19h 34m.
The fastest way to get from Milwaukee to Mechanicsburg is to bus and fly and taxi which takes 5h 51m and costs $230 - $550.
No, there is no direct bus from Milwaukee station to Mechanicsburg. However, there are services departing from Milwaukee Intermodal Station and arriving at E Main St & Arch St WB via Chicago Bus Station and Market Square Transfer Center. The journey, including transfers, takes approximately 19h 34m.
No, there is no direct train from Milwaukee to Mechanicsburg. However, there are services departing from Milwaukee and arriving at Harrisburg via Chicago Union Station and Pittsburgh Amtrak Station. The journey, including transfers, takes approximately 19h 23m.
The distance between Milwaukee and Mechanicsburg is 636 miles. The road distance is 742.1 miles.
The best way to get from Milwaukee to Mechanicsburg without a car is to train which takes 19h 23m and costs $430 - $700.
It takes approximately 7h 36m to get from Milwaukee to Mechanicsburg, including transfers.
Milwaukee to Mechanicsburg bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
Milwaukee to Mechanicsburg train services, operated by Amtrak, depart from Milwaukee station.
The best way to get from Milwaukee to Mechanicsburg is to fly which takes 7h 36m and costs $90 - $600. Alternatively, you can train, which costs $430 - $700 and takes 19h 23m, you could also bus, which costs $130 - $210 and takes 19h 34m.
What companies run services between Milwaukee, WI, USA and Mechanicsburg, Cumberland County, PA, USA?
United Airlines, American Airlines, and Delta fly from General Mitchell International Airport (MKE) to Harrisburg International Airport (MDT) hourly. Alternatively, you can take a train from Milwaukee to E Main St & Arch St WB via Chicago Union Station, Pittsburgh Amtrak Station, Harrisburg, and Market Square Transfer Center in around 19h 23m.
- Website
- united.com
Flights from General Mitchell International Airport to Harrisburg International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $95–550
Flights from Chicago O'Hare International Airport to Lancaster
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $55–320
Flights from Chicago O'Hare International Airport to Harrisburg International Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $55–320
Flights from Chicago O'Hare International Airport to Harrisburg International Airport via Washington Dulles
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $60–330
Flights from General Mitchell International Airport to Philadelphia International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $120–650
Flights from Chicago O'Hare International Airport to Penn State University Park Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $50–310
Flights from Chicago O'Hare International Airport to Penn State University Park Airport via Washington Dulles
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $60–340
- Website
- aa.com
Flights from General Mitchell International Airport to Harrisburg International Airport via Philadelphia International Airport
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $100–550
Flights from General Mitchell International Airport to Harrisburg International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $95–550
Flights from General Mitchell International Airport to Harrisburg International Airport via Charlotte
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- $120–650
Flights from Chicago O'Hare International Airport to Harrisburg International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $55–320
Flights from Chicago O'Hare International Airport to Harrisburg International Airport via Philadelphia International Airport
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $60–340
Flights from General Mitchell International Airport to Philadelphia International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- $110–650
Flights from Chicago O'Hare International Airport to Penn State University Park Airport via Philadelphia International Airport
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $65–350
- Website
- southwest.com
Flights from General Mitchell International Airport to Philadelphia International Airport via Chicago Midway
- Ave. Duration
- 4h 3m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $120–650
Flights from General Mitchell International Airport to Philadelphia International Airport via St. Louis
- Ave. Duration
- 4h 23m
- When
- Saturday, Tuesday, Wednesday, and Sunday
- Estimated price
- $160–800
Flights from General Mitchell International Airport to Philadelphia International Airport via Baltimore
- Ave. Duration
- 4h 35m
- When
- Monday, Thursday, and Friday
- Estimated price
- $120–650
- Website
- delta.com
Flights from General Mitchell International Airport to Harrisburg International Airport via Detroit
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $90–550
Flights from General Mitchell International Airport to Harrisburg International Airport via Atlanta
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $140–700
Flights from Chicago O'Hare International Airport to Harrisburg International Airport via Detroit
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $55–320
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Chicago Union Station to Pittsburgh Amtrak Station
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- $260–410
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Harrisburg
- Ave. Duration
- 5h 25m
- Frequency
- Once daily
- Estimated price
- $130–210
- Website
- Amtrak
Train from 30th Street Station to Harrisburg
- Ave. Duration
- 1h 51m
- Frequency
- Every 2 hours
- Estimated price
- $55–90
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- $15–23
- Website
- Greyhound
Bus from Chicago Bus Station to Baltimore Downtown Bus Station
- Ave. Duration
- 17h 45m
- Frequency
- Twice daily
- Estimated price
- $130–200
- Website
- Greyhound
Bus from Baltimore Downtown Bus Station to Harrisburg Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a week
- Estimated price
- $13–21
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $13–21
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Harrisburg Bus Station
- Ave. Duration
- 15h 55m
- Frequency
- Once daily
- Estimated price
- $120–180
- Schedules at
- Flixbus USA
Bus from State College Regional Airport to Harrisburg Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $14–22
- Schedules at
- Flixbus USA
- Phone
- (866) 912 6224
- [email protected]
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
- Ave. Duration
- 55 min
- Estimated price
- $140–180
Lancaster City Cabs
- Phone
- +1 717-824-4488
- Website
- facebook.com
Want to know more about travelling around United States
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Booking & Getting There
Milwaukee to Mechanicsburg bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Mechanicsburg is 1h ahead of Milwaukee. It is currently 5:22 PM in Milwaukee and 6:22 PM in Mechanicsburg.
Milwaukee to Mechanicsburg train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Milwaukee to Mechanicsburg is 742 miles. It takes approximately 12h 22m to drive from Milwaukee to Mechanicsburg.
There are 132+ hotels available in Mechanicsburg.







