There are 9 ways to get from Milwaukee to Mechanicsburg by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, taxi, train, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly General Mitchell International Airport to Harrisburg International Airport
best- Fly from General Mitchell International Airport (MKE) to Harrisburg International Airport (MDT)plane MKE - MDT
6h 53m$99–566Train (Amtrak)
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain
- Take the train from Pittsburgh Amtrak Station to Harrisburgtrain
19h 23m$254–537Bus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus Greyhound US0150 / ...
- Take the bus from Chicago Bus Station to Harrisburg Bus Stationbus FlixBus N2640 / ...
19h 39m$135–238Drive 737.8 mi
- Drive from Milwaukee to Mechanicsburgcar 737.8 mi
12h 22m$135–195Bus to Chicago O'Hare International Airport, fly to Harrisburg International Airport
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Harrisburg International Airport (MDT)plane ORD - MDT
6h 34m$105–405Bus to Chicago O'Hare International Airport, fly to Lancaster, taxi
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Lancaster (LNS)plane ORD - LNS
- Take the taxi from Lancaster-Airport-LNS to Mechanicsburgtaxi
5h 53m$233–571Fly General Mitchell International Airport to Philadelphia International Airport, train
- Fly from General Mitchell International Airport (MKE) to Philadelphia International Airport (PHL)plane MKE - PHL
- Take the train from 30th Street Station to Harrisburgtrain
8h 3m$186–837Bus to Chicago O'Hare International Airport, fly to Penn State University Park Airport, bus
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Penn State University Park Airport (SCE)plane ORD - SCE
- Take the bus from State College Regional Airport to Harrisburg Bus Stationbus
8h 32m$114–408Bus via Baltimore
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Take the bus from Chicago Bus Station to Baltimore Downtown Bus Stationbus
- Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus
25h 16m$173–302
Milwaukee to Mechanicsburg by train, foot, and bus (Amtrak)
Questions & Answers
The cheapest way to get from Milwaukee to Mechanicsburg is to drive which costs $130 - $200 and takes 12h 22m.
The fastest way to get from Milwaukee to Mechanicsburg is to bus and fly and taxi which takes 5h 53m and costs $230 - $600.
No, there is no direct bus from Milwaukee station to Mechanicsburg. However, there are services departing from Milwaukee Intermodal Station and arriving at E Main St & Arch St WB via Chicago Bus Station and Market Square Transfer Center. The journey, including transfers, takes approximately 19h 39m.
No, there is no direct train from Milwaukee to Mechanicsburg. However, there are services departing from Milwaukee and arriving at Harrisburg via Chicago Union Station and Pittsburgh Amtrak Station. The journey, including transfers, takes approximately 19h 23m.
The distance between Milwaukee and Mechanicsburg is 636 miles. The road distance is 742.1 miles.
The best way to get from Milwaukee to Mechanicsburg without a car is to train which takes 19h 23m and costs $250 - $550.
It takes approximately 6h 53m to get from Milwaukee to Mechanicsburg, including transfers.
Milwaukee to Mechanicsburg bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
Milwaukee to Mechanicsburg train services, operated by Amtrak, depart from Milwaukee station.
The best way to get from Milwaukee to Mechanicsburg is to fly which takes 6h 53m and costs $95 - $600. Alternatively, you can train, which costs $250 - $550 and takes 19h 23m, you could also bus, which costs $130 - $240 and takes 19h 39m.
What companies run services between Milwaukee, WI, USA and Mechanicsburg, Cumberland County, PA, USA?
Delta, American Airlines, and United Airlines fly from General Mitchell International Airport (MKE) to Harrisburg International Airport (MDT) hourly. Alternatively, you can take a train from Milwaukee to E Main St & Arch St WB via Chicago Union Station, Pittsburgh Amtrak Station, Harrisburg, and Market Square Transfer Center in around 19h 23m.
- Website
- aa.com
Flights from General Mitchell International Airport to Harrisburg International Airport via Philadelphia International Airport
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $110–600
Flights from General Mitchell International Airport to Harrisburg International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $100–550
Flights from General Mitchell International Airport to Harrisburg International Airport via Charlotte
- Ave. Duration
- 5h 23m
- When
- Every day
- Estimated price
- $140–650
Flights from Chicago O'Hare International Airport to Harrisburg International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $65–360
Flights from Chicago O'Hare International Airport to Harrisburg International Airport via Charlotte
- Ave. Duration
- 4h 29m
- When
- Monday to Friday
- Estimated price
- $95–440
Flights from Chicago O'Hare International Airport to Harrisburg International Airport via Philadelphia International Airport
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $75–390
Flights from General Mitchell International Airport to Philadelphia International Airport
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $150–750
Flights from General Mitchell International Airport to Philadelphia International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $150–800
Flights from General Mitchell International Airport to Philadelphia International Airport via Reagan Washington
- Ave. Duration
- 4h 32m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–800
Flights from Chicago O'Hare International Airport to Penn State University Park Airport via Philadelphia International Airport
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $80–400
- Website
- united.com
Flights from General Mitchell International Airport to Harrisburg International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $100–550
Flights from Chicago O'Hare International Airport to Harrisburg International Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $65–360
Flights from Chicago O'Hare International Airport to Harrisburg International Airport via Washington Dulles
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $70–370
Flights from Chicago O'Hare International Airport to Lancaster
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $65–360
Flights from Chicago O'Hare International Airport to Penn State University Park Airport
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- $60–340
Flights from Chicago O'Hare International Airport to Penn State University Park Airport via Washington Dulles
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $75–380
- Website
- southwest.com
Flights from General Mitchell International Airport to Philadelphia International Airport via Chicago Midway
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $150–800
Flights from General Mitchell International Airport to Philadelphia International Airport via St. Louis
- Ave. Duration
- 4h 30m
- When
- Sunday, Monday, Thursday, Friday, Tuesday, and Wednesday
- Estimated price
- $210–950
Flights from General Mitchell International Airport to Philadelphia International Airport via Nashville
- Ave. Duration
- 4h 25m
- When
- Tuesday and Wednesday
- Estimated price
- $210–950
- Website
- delta.com
Flights from General Mitchell International Airport to Harrisburg International Airport via Detroit
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $95–550
Flights from General Mitchell International Airport to Harrisburg International Airport via Atlanta
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $160–750
Flights from Chicago O'Hare International Airport to Harrisburg International Airport via Detroit
- Ave. Duration
- 3h 45m
- When
- Saturday
- Estimated price
- $65–360
Flights from Chicago O'Hare International Airport to Harrisburg International Airport via Atlanta
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $110–480
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $27–60
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Pittsburgh Amtrak Station
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- $150–320
- Website
- https://www.amtrak.com/home.html
Train from Pittsburgh Amtrak Station to Harrisburg
- Ave. Duration
- 5h 25m
- Frequency
- Once daily
- Estimated price
- $75–160
- Website
- https://www.amtrak.com/home.html
Train from 30th Street Station to Harrisburg
- Ave. Duration
- 1h 51m
- Frequency
- Every 2 hours
- Estimated price
- $30–70
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $14–27
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Baltimore Downtown Bus Station
- Ave. Duration
- 17h 45m
- Frequency
- Twice daily
- Estimated price
- $120–230
- Website
- https://www.greyhound.com/
Bus from Baltimore Downtown Bus Station to Harrisburg Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $12–24
- Website
- https://www.greyhound.com/
- Website
- greyhound.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Schedules at
- greyhound.com
Bus from Chicago Bus Station to Baltimore Downtown Bus Station
- Ave. Duration
- 17h 40m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Bus from Baltimore Downtown Bus Station to Harrisburg Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Schedules at
- greyhound.com
- Website
- flixbus.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 3 times a day
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to Harrisburg Bus Station
- Ave. Duration
- 15h 55m
- Frequency
- Once daily
- Schedules at
- flixbus.com
Bus from State College Regional Airport to Harrisburg Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Schedules at
- flixbus.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $14–24
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to Harrisburg Bus Station
- Ave. Duration
- 15h 55m
- Frequency
- Once daily
- Estimated price
- $120–210
- Schedules at
- flixbus.com
Bus from State College Regional Airport to Harrisburg Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Schedules at
- flixbus.com
- Phone
- (866) 912 6224
- [email protected]
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- https://www.coachusa.com/wisconsin-coach?gad_source=1&gclid=CjwKCAiAt4C-BhBcEiwA8Kp0Cc3RRg_kOdc3CzsoiFSe4BX-r10-kIOeuDNMfsAKsG5uubvoAmxcrRoC5LwQAvD_BwE
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- https://www.coachusa.com/wisconsin-coach?gad_source=1&gclid=CjwKCAiAt4C-BhBcEiwA8Kp0Cc3RRg_kOdc3CzsoiFSe4BX-r10-kIOeuDNMfsAKsG5uubvoAmxcrRoC5LwQAvD_BwE
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- https://www.coachusa.com/wisconsin-coach?gad_source=1&gclid=CjwKCAiAt4C-BhBcEiwA8Kp0Cc3RRg_kOdc3CzsoiFSe4BX-r10-kIOeuDNMfsAKsG5uubvoAmxcrRoC5LwQAvD_BwE
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- https://www.coachusa.com/wisconsin-coach?gad_source=1&gclid=CjwKCAiAt4C-BhBcEiwA8Kp0Cc3RRg_kOdc3CzsoiFSe4BX-r10-kIOeuDNMfsAKsG5uubvoAmxcrRoC5LwQAvD_BwE
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Every 2 hours
- Schedules at
- coachusaairportexpress.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Every 2 hours
- Schedules at
- coachusaairportexpress.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Every 2 hours
- Schedules at
- coachusaairportexpress.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Every 2 hours
- Schedules at
- coachusaairportexpress.com
- Ave. Duration
- 57 min
- Estimated price
- $130–170
Lancaster City Cabs
- Phone
- +1 717-824-4488
- Website
- facebook.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Milwaukee to Mechanicsburg bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Mechanicsburg is 1h ahead of Milwaukee. It is currently 10:39 AM in Milwaukee and 11:39 AM in Mechanicsburg.
Milwaukee to Mechanicsburg train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Milwaukee to Mechanicsburg is 742 miles. It takes approximately 12h 22m to drive from Milwaukee to Mechanicsburg.
There are 163+ hotels available in Mechanicsburg.







