There are 6 ways to get from Milwaukee to Saint Charles by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from General Mitchell International Airport
best- Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane MKE - STL
3h 47m$486–856Bus
cheapest- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus Greyhound US0150 / ...
- Take the bus from Chicago Bus Station to St Louis Bus Stationbus FlixBus 2510 / ...
10h 33m$66–113Train (Amtrak)
- Take the train from Milwaukee to Chicago Union Stationtrain Hiawatha Service / ...
- Take the train from Chicago Union Station to St. Louistrain Lincoln Service / ...
8h 40m$122–250Drive 385.2 mi
- Drive from Milwaukee to Saint Charlescar 385.2 mi
6h 34m$71–102Bus to Chicago O'Hare International Airport, fly
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane ORD - STL
5h 11m$312–745Train to Chicago Midway International Airport, fly
- Take the train from Milwaukee to Chicago Union Stationtrain
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
5h 39m$117–618
Milwaukee to Saint Charles by train and bus (Amtrak)
Questions & Answers
The cheapest way to get from Milwaukee to Saint Charles is to bus which costs $65 - $120 and takes 10h 33m.
The fastest way to get from Milwaukee to Saint Charles is to fly which takes 3h 47m and costs $480 - $900.
No, there is no direct bus from Milwaukee station to Saint Charles. However, there are services departing from Milwaukee Intermodal Station and arriving at 4375 Rider Trail North Sb via Chicago Bus Station, Civic Center Transit Center and North Hanley Transit Center. The journey, including transfers, takes approximately 10h 33m.
No, there is no direct train from Milwaukee to Saint Charles station. However, there are services departing from Milwaukee and arriving at NORTH HANLEY station via Chicago Union Station and CIVIC CENTER station. The journey, including transfers, takes approximately 8h 40m.
The distance between Milwaukee and Saint Charles is 341 miles. The road distance is 387.4 miles.
The best way to get from Milwaukee to Saint Charles without a car is to train which takes 8h 40m and costs $120 - $250.
It takes approximately 3h 47m to get from Milwaukee to Saint Charles, including transfers.
Milwaukee to Saint Charles bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
Milwaukee to Saint Charles train services, operated by Amtrak, depart from Milwaukee station.
The best way to get from Milwaukee to Saint Charles is to fly which takes 3h 47m and costs $480 - $900. Alternatively, you can train, which costs $120 - $250 and takes 8h 40m, you could also bus, which costs $65 - $120 and takes 10h 33m.
What companies run services between Milwaukee, WI, USA and Saint Charles, MO, USA?
Southwest Airlines flies from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL) twice daily. Alternatively, you can take a train from Milwaukee to 4375 Rider Trail North Sb via Chicago Union Station, St. Louis, CIVIC CENTER station, NORTH HANLEY station, and North Hanley Transit Center in around 8h 40m.
- Website
- southwest.com
Flights from General Mitchell International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $100–650
Flights from General Mitchell International Airport to Lambert–St. Louis International Airport via Chicago Midway International Airport
- Ave. Duration
- 3h 5m
- When
- Sunday
- Estimated price
- $100–650
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $80–550
- Website
- united.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $60–410
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $60–410
- Website
- gojetairlines.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $60–410
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $27–60
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $27–60
- Website
- https://www.amtrak.com/home.html
#mediaviewer/File:Super_Dome_car.jpg "Hiawatha dome car")
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $14–27
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $14–23
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- $50–85
- Schedules at
- flixbus.com
- Phone
- (866) 912 6224
- [email protected]
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- https://www.coachusa.com/wisconsin-coach?gad_source=1&gclid=CjwKCAiAt4C-BhBcEiwA8Kp0Cc3RRg_kOdc3CzsoiFSe4BX-r10-kIOeuDNMfsAKsG5uubvoAmxcrRoC5LwQAvD_BwE
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Milwaukee to Saint Charles bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Milwaukee to Saint Charles train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Milwaukee to Saint Charles is 387 miles. It takes approximately 6h 34m to drive from Milwaukee to Saint Charles.
There are 186+ hotels available in Saint Charles.