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How to get fromMilwaukee to Sanibelby plane, bus (Greyhound, Flixbus), train, bus, or car

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There are 7 ways to get from Milwaukee to Sanibel by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from General Mitchell International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Ft. Myers (RSW)plane plane MKE - RSW
    4h 47m
    $242–887

  2. Bus to Chicago O'Hare International Airport, fly

    cheapest
    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Ft. Myers (RSW)plane plane ORD - RSW
    6h 23m
    $218–676

  3. Bus

    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    4. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    34h 1m
    $236–427

  4. Train, bus

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Tampatrain train
    3. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    2d
    $601–1,256

  5. Drive 1,330.3 mi

    1. Drive from Milwaukee to Sanibelcar car 1,330.3 mi
    24h 33m
    $243–351

  6. Train to Chicago Midway International Airport, fly

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Ft. Myers (RSW)plane plane MDW - RSW
    6h 39m
    $239–845

  7. Bus to Dane County Regional Airport-Truax Field, fly

    1. Take the bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.bus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Ft. Myers (RSW)plane plane MSN - RSW
    7h 4m
    $263–908

General Mitchell International Airport (MKE) to Ft. Myers (RSW) flights

Calendar61Weekly Planes
Duration4h 53mAverage Duration
Ticket$175Cheapest Price
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Questions & Answers

Map of how to get from Milwaukee to Sanibel.ExpandLaunch map view
  • Distance: 1,218.3 mi
  • Duration: 4h 47m

What companies run services between Milwaukee, WI, USA and Sanibel, FL, USA?

Southwest Airlines, American Airlines, and Delta fly from General Mitchell International Airport (MKE) to Ft. Myers (RSW) every 3 hours. Alternatively, you can take a bus from Milwaukee Intermodal Station to Sanibel via Chicago Bus Station, Atlanta Bus Station, Tampa Bus Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 34h 1m.

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