Rome2Rio

How to get fromMilwaukee to Santa Anaby plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or train

Find Transport to Santa Ana

See all options

There are 6 ways to get from Milwaukee to Santa Ana by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly General Mitchell International Airport to John Wayne Airport Orange County

    best
    1. Fly from General Mitchell International Airport (MKE) to John Wayne Airport Orange County (SNA)plane plane MKE - SNA
    7h 24m
    $251–1,037

  2. Bus to Chicago O'Hare International Airport, fly to John Wayne Airport Orange County

    cheapest
    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to John Wayne Airport Orange County (SNA)plane plane ORD - SNA
    7h 32m
    $197–676

  3. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train Hiawatha Service / ...
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train Southwest Chief
    46h 6m
    $1,253–1,981

  4. Bus

    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to El Monte Bus Stopbus bus
    4. Take the bus from El Monte to Santa Anabus bus
    2d 3h
    $429–639

  5. Drive  2,034.7 mi

    1. Drive from Milwaukee to Santa Anacar car 2,034.7 mi
    32h 25m
    $372–537

  6. Fly General Mitchell International Airport to San Diego International Airport, train

    1. Fly from General Mitchell International Airport (MKE) to San Diego International Airport (SAN)plane plane MKE - SAN
    2. Take the train from San Diego to Santa Anatrain train
    9h 16m
    $224–837

Milwaukee to Santa Ana by train (Amtrak)

Calendar7Weekly Trains
Duration46h 6mAverage Duration
Ticket$1,253Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Milwaukee to Santa Ana.ExpandLaunch map view
  • Distance: 1,747.5 mi
  • Duration: 7h 24m

What companies run services between Milwaukee, WI, USA and Santa Ana, CA, USA?

Southwest Airlines, American Airlines, and two other airlines fly from General Mitchell International Airport (MKE) to John Wayne Airport Orange County (SNA) hourly. Alternatively, you can take a train from Milwaukee to Santa Ana via Chicago Union Station and Fullerton Amtrak Station in around 46h 6m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There