There are 7 ways to get from Milwaukee to Santa Ana by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly General Mitchell International Airport to John Wayne Airport Orange County
best- Fly from General Mitchell International Airport (MKE) to John Wayne Airport Orange County (SNA)plane MKE - SNA
7h 24m$241–1,037Bus to Chicago O'Hare International Airport, fly to Los Angeles International Airport, train
cheapest- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Los Angeles International Airport (LAX)plane ORD - LAX
- Take the train from Los Angeles to Santa Anatrain
9h 55m$173–435Train (Amtrak)
- Take the train from Milwaukee to Chicago Union Stationtrain Hiawatha Service / ...
- Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain Southwest Chief
46h 4m$527–1,358Bus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to El Monte Bus Stopbus
- Take the bus from El Monte to Santa Anabus
2d 3h$373–603Drive 2,034.7 mi
- Drive from Milwaukee to Santa Anacar 2,034.7 mi
32h 25m$372–537Bus to Chicago O'Hare International Airport, fly to John Wayne Airport Orange County
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to John Wayne Airport Orange County (SNA)plane ORD - SNA
7h 21m$257–496Fly General Mitchell International Airport to San Diego International Airport, train
- Fly from General Mitchell International Airport (MKE) to San Diego International Airport (SAN)plane MKE - SAN
- Take the train from San Diego to Santa Anatrain
9h 16m$196–862
Milwaukee to Santa Ana by train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Milwaukee to Santa Ana is to bus and fly and train which costs $170 - $440 and takes 9h 55m.
The fastest way to get from Milwaukee to Santa Ana is to bus and fly which takes 7h 21m and costs $250 - $500.
No, there is no direct bus from Milwaukee station to Santa Ana. However, there are services departing from Milwaukee Intermodal Station and arriving at Santa Ana via Chicago Bus Station, St Louis Bus Station, El Monte Station Upper Level and El Monte. The journey, including transfers, takes approximately 2 days 3h.
No, there is no direct train from Milwaukee to Santa Ana. However, there are services departing from Milwaukee and arriving at Santa Ana via Chicago Union Station and Fullerton Amtrak Station. The journey, including transfers, takes approximately 46h 4m.
The distance between Milwaukee and Santa Ana is 1758 miles. The road distance is 2046.6 miles.
The best way to get from Milwaukee to Santa Ana without a car is to train which takes 46h 4m and costs $500 - $1,400.
It takes approximately 7h 24m to get from Milwaukee to Santa Ana, including transfers.
Milwaukee to Santa Ana bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
Milwaukee to Santa Ana train services, operated by Amtrak, depart from Milwaukee station.
The best way to get from Milwaukee to Santa Ana is to fly which takes 7h 24m and costs $240 - $1,100. Alternatively, you can train, which costs $500 - $1,400 and takes 46h 4m, you could also bus, which costs $370 - $650 and takes 2 days 3h.
What companies run services between Milwaukee, WI, USA and Santa Ana, CA, USA?
Southwest Airlines, United Airlines, and two other airlines fly from General Mitchell International Airport (MKE) to John Wayne Airport Orange County (SNA) hourly. Alternatively, you can take a train from Milwaukee to Santa Ana via Chicago Union Station and Fullerton Amtrak Station in around 46h 4m.
- Website
- united.com
Flights from General Mitchell International Airport to John Wayne Airport Orange County via Denver
- Ave. Duration
- 6h 55m
- When
- Every day
- Estimated price
- $210–1,000
Flights from General Mitchell International Airport to John Wayne Airport Orange County via Chicago O'Hare International Airport
- Ave. Duration
- 8h 12m
- When
- Every day
- Estimated price
- $220–1,000
Flights from Chicago O'Hare International Airport to John Wayne Airport Orange County
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $130–650
Flights from Chicago O'Hare International Airport to John Wayne Airport Orange County via Denver
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $140–650
Flights from General Mitchell International Airport to San Diego International Airport via Denver
- Ave. Duration
- 6h 26m
- When
- Every day
- Estimated price
- $170–800
Flights from Chicago O'Hare International Airport to Los Angeles International Airport
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $85–390
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $20–50
- Website
- Amtrak
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Once daily
- Estimated price
- $500–1,300
- Website
- Amtrak
Train from San Diego to Santa Ana
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- $22–55
- Website
- Amtrak
Train from Los Angeles to Santa Ana
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $8–21
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- $13–22
- Website
- Greyhound
Bus from St Louis Bus Station to El Monte Bus Stop
- Ave. Duration
- 40h 10m
- Frequency
- Once daily
- Estimated price
- $290–470
- Website
- Greyhound
Want to know more about travelling around United States
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Booking & Getting There
Milwaukee to Santa Ana bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Santa Ana is 2h behind Milwaukee. It is currently 2:14 PM in Milwaukee and 12:14 PM in Santa Ana.
Milwaukee to Santa Ana train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Milwaukee to Santa Ana is 2047 miles. It takes approximately 32h 25m to drive from Milwaukee to Santa Ana.
Book your Milwaukee to Santa Ana train tickets online with Omio.
Book your Milwaukee to Santa Ana bus tickets online with Omio.
There are 1606+ hotels available in Santa Ana.






