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How to get fromMilwaukee to Senecaby plane, taxi, bus, train (Amtrak), car, or train

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There are 10 ways to get from Milwaukee to Seneca by plane, taxi, bus, train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly General Mitchell International Airport to Greenville–Spartanburg International Airport, taxi

    best
    1. Fly from General Mitchell International Airport (MKE) to Greenville–Spartanburg International Airport (GSP)plane plane MKE - GSP
    2. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    6h 12m
    $282–1,022

  2. Bus to Chicago O'Hare International Airport, fly to Asheville Regional Airport, drive

    cheapest
    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    3. Drive from Asheville-Airport-AVL to Senecacar car
    6h 31m
    $100–370

  3. Bus, taxi

    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Flying J - Commercebus bus
    4. Take the taxi from Flying J - Commerce to Senecataxi taxi
    23h 20m
    $247–399

  4. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Charlottesvilletrain train
    3. Take the train from Charlottesville to Clemson Amtrak Stationtrain train
    33h 36m
    $731–1,142

  5. Drive  765.2 mi

    1. Drive from Milwaukee to Senecacar car 765.2 mi
    14h 52m
    $140–202

  6. Bus to Chicago O'Hare International Airport, fly to Greenville–Spartanburg International Airport, taxi

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane plane ORD - GSP
    3. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    5h 53m
    $253–711

  7. Fly General Mitchell International Airport to Hartsfield-Jackson Atlanta International Airport, bus, taxi

    1. Fly from General Mitchell International Airport (MKE) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane MKE - ATL
    2. Take the bus from Atlanta to Flying J - Commercebus bus
    3. Take the taxi from Flying J - Commerce to Senecataxi taxi
    8h 6m
    $622–1,275

  8. Fly General Mitchell International Airport to Charlotte Douglas International Airport, train

    1. Fly from General Mitchell International Airport (MKE) to Charlotte Douglas International Airport (CLT)plane plane MKE - CLT
    2. Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain train
    8h 59m
    $255–1,008

  9. Bus, taxi via Chicago O'Hare Airport (ORD)

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Flying J - Commercebus bus
    4. Take the taxi from Flying J - Commerce to Senecataxi taxi
    24h 22m
    $293–422

  10. Train via Cary (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    4. Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain train
    35h 17m
    $786–1,312

General Mitchell International Airport (MKE) to Greenville–Spartanburg International Airport (GSP) flights

Calendar102Weekly Planes
Duration5h 24mAverage Duration
Ticket$152Cheapest Price
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Comparing Your Travel Options

Map of how to get from Milwaukee to Seneca.ExpandLaunch map view
  • Distance: 691.5 mi
  • Duration: 6h 12m

What companies run services between Milwaukee, WI, USA and Seneca, SC, USA?

You can take a train from Milwaukee to Seneca via Chicago Union Station, Charlottesville, and Clemson Amtrak Station in around 33h 36m.

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