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How to get fromMilwaukee to South Carolinaby plane, taxi, train (Amtrak), car, bus, or train

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There are 9 ways to get from Milwaukee to South Carolina by plane, taxi, train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly General Mitchell International Airport to Charlotte Douglas International Airport, taxi

    best
    1. Fly from General Mitchell International Airport (MKE) to Charlotte Douglas International Airport (CLT)plane plane MKE - CLT
    2. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    4h 8m
    $232–912

  2. Bus to Chicago O'Hare International Airport, fly to Charleston International Airport

    cheapest
    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Charleston International Airport (CHS)plane plane ORD - CHS
    6h 13m
    $125–463

  3. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    31h 8m
    $458–946

  4. Drive 961 mi

    1. Drive from Milwaukee to Charlestoncar car 961 mi
    17h 38m
    $176–254

  5. Bus to Chicago O'Hare International Airport, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane plane ORD - GSP
    5h 7m
    $168–636

  6. Bus to Chicago O'Hare International Airport, fly to Charlotte Douglas International Airport, taxi

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Charlotte Douglas International Airport (CLT)plane plane ORD - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    5h 25m
    $248–551

  7. Bus to Chicago O'Hare International Airport, fly to Asheville Regional Airport, taxi

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    3. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    5h 43m
    $238–551

  8. Bus to Chicago O'Hare International Airport, fly to Columbia

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Columbia (CAE)plane plane ORD - CAE
    6h 20m
    $210–943

  9. Train to Chicago Midway International Airport, fly to Charleston International Airport

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Charleston International Airport (CHS)plane plane MDW - CHS
    6h 30m
    $135–616

General Mitchell International Airport (MKE) to Charlotte Douglas International Airport (CLT) flights

Calendar52Weekly Planes
Duration3h 49mAverage Duration
Ticket$154Cheapest Price
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Questions & Answers

Map of how to get from Milwaukee to South Carolina.ExpandLaunch map view
  • Distance: 686.2 mi
  • Duration: 4h 8m

What companies run services between Milwaukee, WI, USA and South Carolina, USA?

You can take a train from Milwaukee to Charleston via Chicago Union Station, Petersburg Amtrak Station, and Charleston Amtrak Station in around 31h 8m.

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