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How to get fromMilwaukee to Spartanburgby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, or bus (Greyhound)

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There are 8 ways to get from Milwaukee to Spartanburg by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly General Mitchell International Airport to Greenville–Spartanburg International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Greenville–Spartanburg International Airport (GSP)plane plane MKE - GSP
    5h 25m
    $207–890

  2. Bus to Chicago O'Hare International Airport, fly to Asheville Regional Airport, drive

    cheapest
    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    3. Drive from Asheville-Airport-AVL to Spartanburgcar car
    5h 45m
    $99–396

  3. Bus

    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Spartanburgbus bus
    21h 19m
    $181–332

  4. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    4. Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain train
    33h 19m
    $452–915

  5. Drive 761.2 mi

    1. Drive from Milwaukee to Spartanburgcar car 761.2 mi
    14h 25m
    $139–201

  6. Bus to Chicago O'Hare International Airport, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane plane ORD - GSP
    5h 16m
    $180–661

  7. Fly General Mitchell International Airport to Charlotte Douglas International Airport, train

    1. Fly from General Mitchell International Airport (MKE) to Charlotte Douglas International Airport (CLT)plane plane MKE - CLT
    2. Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain train
    7h 11m
    $180–876

  8. Bus via Chicago O'Hare Airport (ORD)

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Spartanburgbus bus
    23h 58m
    $249–351

Milwaukee to Spartanburg by train (Amtrak)

Calendar7Weekly Trains
Duration33h 19mAverage Duration
Ticket$452Cheapest Price
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Questions & Answers

Map of how to get from Milwaukee to Spartanburg.ExpandLaunch map view
  • Distance: 661.4 mi
  • Duration: 5h 25m

What companies run services between Milwaukee, WI, USA and Spartanburg, SC, USA?

Southwest Airlines, Delta, and two other airlines fly from General Mitchell International Airport (MKE) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a bus from Milwaukee Intermodal Station to Spartanburg via Chicago Bus Station, Atlanta Bus Station, and Spartanburg in around 21h 19m.

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