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How to get fromMilwaukee to Syracuseby plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, train, or bus (Flixbus)

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There are 10 ways to get from Milwaukee to Syracuse by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly General Mitchell International Airport to Syracuse Hancock International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Syracuse Hancock International Airport (SYR)plane plane MKE - SYR
    7h 5m
    $173–960

  2. Bus

    cheapest
    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Syracuse Bus Stationbus bus
    17h 35m
    $113–235

  3. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train Hiawatha Service / ...
    2. Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain train Lake Shore Limited
    15h 27m
    $237–496

  4. Drive 764.8 mi

    1. Drive from Milwaukee to Syracusecar car 764.8 mi
    13h 12m
    $140–202

  5. Bus to Chicago O'Hare International Airport, fly to Syracuse Hancock International Airport

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Syracuse Hancock International Airport (SYR)plane plane ORD - SYR
    6h 29m
    $159–699

  6. Fly General Mitchell International Airport to Rochester, train

    1. Fly from General Mitchell International Airport (MKE) to Rochester (ROC)plane plane MKE - ROC
    2. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    7h 9m
    $191–1,044

  7. Bus to Chicago O'Hare International Airport, fly to Rochester, train

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (ROC)plane plane ORD - ROC
    3. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    7h 3m
    $177–833

  8. Train to Chicago Midway International Airport, fly to Rochester, train

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)plane plane MDW - ROC
    3. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    7h 21m
    $201–1,006

  9. Bus to Chicago O'Hare International Airport, fly to Buffalo Niagara International Airport, bus

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane plane ORD - BUF
    3. Take the bus from Buffalo Niagara International Airport to Syracuse Bus Stationbus bus
    8h
    $235–431

  10. Bus via Toronto

    1. Take the bus from Milwaukee Intermodal Station to Detroit Bus Stationbus bus
    2. Take the bus from Detroit Bus Station to Torontobus bus
    3. Take the bus from Toronto to Syracusebus bus
    22h 15m
    $135–323

Milwaukee to Syracuse by train (Amtrak)

Calendar14Weekly Trains
Duration15h 27mAverage Duration
Ticket$237Cheapest Price
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Questions & Answers

Map of how to get from Milwaukee to Syracuse.ExpandLaunch map view
  • Distance: 614.4 mi
  • Duration: 7h 5m

What companies run services between Milwaukee, WI, USA and Syracuse, NY, USA?

Delta, United Airlines, and American Airlines fly from General Mitchell International Airport (MKE) to Syracuse Hancock International Airport (SYR) hourly. Alternatively, you can take a train from Milwaukee to Syracuse Regional Transportation Center via Chicago Union Station in around 15h 27m.

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