There are 7 ways to get from Milwaukee to Winston-Salem by plane, bus (Flixbus, Greyhound), car, bus, or bus (Greyhound, Flixbus, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly General Mitchell International Airport to Piedmont Triad International Airport
best- Fly from General Mitchell International Airport (MKE) to Piedmont Triad International Airport (GSO)plane MKE - GSO
6h 24m$111–575Bus to Chicago O'Hare International Airport, fly to Piedmont Triad International Airport
cheapest- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 1 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO)plane ORD - GSO
5h 57m$107–374Bus via Columbus
- Take the bus from Milwaukee Intermodal Station to Columbusbus FlixBus 2511
- Take the bus from Columbus to Winston Salem(Trans Center)bus Greyhound US0140
20h 23m$150–230Drive 764.3 mi
- Drive from Milwaukee to Winston-Salemcar 764.3 mi
14h 24m$131–189Fly General Mitchell International Airport to Charlotte Douglas International Airport, bus
- Fly from General Mitchell International Airport (MKE) to Charlotte Douglas International Airport (CLT)plane MKE - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
6h 40m$170–879Bus to Chicago O'Hare International Airport, fly to Charlotte Douglas International Airport, bus
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 1 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Charlotte Douglas International Airport (CLT)plane ORD - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
8h 10m$141–558Bus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
- Take the bus from Chicago Union Station to Toledobus
- Take the bus from Toledo Bus Stop to Winston Salem(Trans Center)bus
20h 42m
Milwaukee to Winston-Salem by bus
Comparing Your Travel Options
The cheapest way to get from Milwaukee to Winston-Salem is to drive which costs $130 - $190 and takes 14h 24m.
The fastest way to get from Milwaukee to Winston-Salem is to bus and fly which takes 5h 57m and costs $100 - $380.
No, there is no direct bus from Milwaukee station to Winston-Salem. However, there are services departing from Milwaukee Intermodal Station and arriving at Winston Salem(Trans Center) via E Main St & S High St and Columbus. The journey, including transfers, takes approximately 20h 23m.
The distance between Milwaukee and Winston-Salem is 669 miles. The road distance is 768.8 miles.
The best way to get from Milwaukee to Winston-Salem without a car is to bus via Columbus which takes 20h 23m and costs $150 - $230.
It takes approximately 6h 24m to get from Milwaukee to Winston-Salem, including transfers.
Milwaukee to Winston-Salem bus services, operated by Flixbus USA, depart from Milwaukee Intermodal Station.
The best way to get from Milwaukee to Winston-Salem is to fly which takes 6h 24m and costs $110 - $600. Alternatively, you can bus via Columbus, which costs $150 - $230 and takes 20h 23m.
Milwaukee to Winston-Salem bus services, operated by Flixbus USA, arrive at Columbus station.
Winston-Salem is 1h ahead of Milwaukee. It is currently 11:15 AM in Milwaukee and 12:15 PM in Winston-Salem.
What companies run services between Milwaukee, WI, USA and Winston-Salem, NC, USA?
Delta, United Airlines, and American Airlines fly from General Mitchell International Airport (MKE) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a bus from Milwaukee Intermodal Station to Winston Salem(Trans Center) via Columbus, E Main St & S High St, S Grant Ave & E Mound St, and Columbus in around 20h 23m.
- Website
- aa.com
Flights from General Mitchell International Airport to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 37m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $100–550
Flights from General Mitchell International Airport to Piedmont Triad International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $90–550
Flights from General Mitchell International Airport to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 5h 23m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
Flights from General Mitchell International Airport to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 8h 17m
- When
- Sunday
- Estimated price
- $120–650
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $50–310
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $55–320
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $65–350
Flights from General Mitchell International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $150–850
Flights from Chicago O'Hare International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- $85–490
Flights from Chicago O'Hare International Airport to Charlotte Douglas International Airport via Louisville
- Ave. Duration
- 4h 3m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $90–500
Flights from Chicago O'Hare International Airport to Charlotte Douglas International Airport via Piedmont Triad International Airport
- Ave. Duration
- 4h 3m
- When
- Monday, Tuesday, Wednesday, and Saturday
- Estimated price
- $90–550
- Website
- delta.com
Flights from General Mitchell International Airport to Piedmont Triad International Airport via Detroit
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $95–550
Flights from General Mitchell International Airport to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $120–600
Flights from General Mitchell International Airport to Piedmont Triad International Airport via New York La Guardia
- Ave. Duration
- 6h 43m
- When
- Every day
- Estimated price
- $130–650
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $70–350
Flights from General Mitchell International Airport to Charlotte Douglas International Airport via Detroit
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $160–900
Flights from General Mitchell International Airport to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $180–950
- Website
- united.com
Flights from General Mitchell International Airport to Piedmont Triad International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $90–550
Flights from General Mitchell International Airport to Piedmont Triad International Airport via Newark
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $130–650
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport
- Ave. Duration
- 2h 3m
- When
- Every day
- Estimated price
- $50–310
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $65–340
Flights from General Mitchell International Airport to Charlotte Douglas International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $150–850
Flights from Chicago O'Hare International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 13m
- When
- Every day
- Estimated price
- $85–490
- Website
- southwest.com
Flights from General Mitchell International Airport to Charlotte Douglas International Airport via Chicago Midway
- Ave. Duration
- 4h 2m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $150–850
Flights from General Mitchell International Airport to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 4h 30m
- When
- Tuesday and Wednesday
- Estimated price
- $170–900
Flights from General Mitchell International Airport to Charlotte Douglas International Airport via Baltimore
- Ave. Duration
- 4h 30m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $190–1,000
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Milwaukee Intermodal Station to Columbus
- Ave. Duration
- 9h 50m
- Frequency
- Twice daily
- Estimated price
- $70–110
- Schedules at
- Flixbus USA
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 5 times a day
- Estimated price
- $14–21
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Columbus to Winston Salem(Trans Center)
- Ave. Duration
- 9h 20m
- Frequency
- Twice daily
- Estimated price
- $75–120
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- 4 times a day
- Estimated price
- $14–21
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- 4 times a day
- Estimated price
- $14–21
- Website
- Greyhound
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $16–25
- Website
- Greyhound
Bus from Toledo Bus Stop to Winston Salem(Trans Center)
- Ave. Duration
- 13h
- Frequency
- Twice daily
- Estimated price
- $100–160
- Website
- Greyhound
- Phone
- (866) 912 6224
- [email protected]
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 1 Departures
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 1 Departures
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Chicago Union Station to Toledo
- Ave. Duration
- 3h 58m
- Frequency
- Twice a week
- Website
- Amtrak
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Booking & Getting There
Yes, the driving distance between Milwaukee to Winston-Salem is 769 miles. It takes approximately 14h 24m to drive from Milwaukee to Winston-Salem.
Book your Milwaukee to Winston-Salem bus tickets online with Omio.
There are 151+ hotels available in Winston-Salem.








