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How to get fromMinneapolis Airport (MSP) to Charlestonby plane, train (Amtrak), car, train, or bus

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There are 6 ways to get from Minneapolis Airport (MSP) to Charleston by plane, train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Charleston International Airport

    best
    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Charleston International Airport (CHS)plane plane MSP - CHS
    4h 18m
    $127–588

  2. Train (Amtrak)

    1. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    38h 36m
    $532–1,152

  3. Drive 1,278.3 mi

    1. Drive from Minneapolis-Airport-MSP to Charlestoncar car 1,278.3 mi
    22h 40m
    $234–337

  4. Fly to Hilton Head Airport, drive

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Hilton Head Airport (HHH)plane plane MSP - HHH
    2. Drive from Hilton Head Airport (HHH) to Charlestoncar car
    7h
    $137–580

  5. Fly to Savannah, train

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Savannah (SAV)plane plane MSP - SAV
    2. Take the train from Savannah Station to Charleston Amtrak Stationtrain train
    7h 14m
    $235–873

  6. Fly to Myrtle Beach, bus

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Myrtle Beach (MYR)plane plane MSP - MYR
    2. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    7h 55m
    $129–518

Minneapolis–Saint Paul International Airport (MSP) to Charleston International Airport (CHS) flights

Calendar19Weekly Planes
Duration4h 40mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

Map of how to get from Minneapolis Airport (MSP) to Charleston.ExpandLaunch map view
  • Distance: 1,101.6 mi
  • Duration: 4h 18m

What companies run services between Minneapolis Airport (MSP), USA and Charleston, SC, USA?

Delta and Southwest Airlines fly from Minneapolis–Saint Paul International Airport (MSP) to Charleston International Airport (CHS) 3 times a day. Alternatively, you can take a bus from MSP Terminal 1 Transit Station to Charleston via Union Depot & Wacouta Station, St. Paul-Minneapolis, Chicago Union Station, Petersburg Amtrak Station, and Charleston Amtrak Station in around 38h 36m.

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