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How to get fromMinneapolis Airport (MSP) to Florenceby plane, bus (Greyhound, Flixbus), train, bus, or car

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There are 5 ways to get from Minneapolis Airport (MSP) to Florence by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Regional Airport

    best
    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Florence Regional Airport (FLO)plane plane MSP - FLO
    4h 46m
    $122–545

  2. Bus

    1. Take the bus from Saint Paul Union Depot to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus
    33h 47m
    $202–418

  3. Train, bus

    1. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    38h 32m
    $466–1,020

  4. Drive 1,236.5 mi

    1. Drive from Minneapolis Airport (MSP) to Florencecar car 1,236.5 mi
    22h 30m
    $226–326

  5. Fly to Charleston International Airport, train

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Charleston International Airport (CHS)plane plane MSP - CHS
    2. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    7h 29m
    $158–655

Minneapolis Airport (MSP) to Florence by bus

Calendar14Weekly Buses
Duration33h 47mAverage Duration
Ticket$202Cheapest Price
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Questions & Answers

Map of how to get from Minneapolis Airport (MSP) to Florence.ExpandLaunch map view
  • Distance: 1,029.6 mi
  • Duration: 4h 46m

What companies run services between Minneapolis Airport (MSP), USA and Florence, SC, USA?

American Airlines, Sun Country Airlines, and Delta fly from Minneapolis–Saint Paul International Airport (MSP) to Florence Regional Airport (FLO) 4 times a day. Alternatively, you can take a bus from MSP Terminal 1 Transit Station to Florence Bus Station via Union Depot Station & Terminal, Saint Paul Union Depot, Chicago Bus Station, and Atlanta Bus Station in around 33h 47m.

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