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How to get fromMinneapolis Airport (MSP) to Louisvilleby plane, bus (Greyhound, Flixbus, Amtrak), train, bus, car, or bus (Amtrak)

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There are 6 ways to get from Minneapolis Airport (MSP) to Louisville by plane, bus (Greyhound, Flixbus, Amtrak), train, bus, car, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louisville International Airport

    best
    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Louisville International Airport (SDF)plane plane MSP - SDF
    3h 5m
    $119–644

  2. Bus

    cheapest
    1. Take the bus from Saint Paul Union Depot to Chicago Bus Stationbus bus Greyhound US0150
    2. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    17h 31m
    $112–182

  3. Train, bus (Amtrak)

    1. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    18h 16m
    $204–448

  4. Drive 699.7 mi

    1. Drive from Minneapolis Airport (MSP) to Louisvillecar car 699.7 mi
    11h 45m
    $128–185

  5. Fly to Blue Grass Airport, drive

    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Blue Grass Airport (LEX)plane plane MSP - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    3h 15m
    $189–961

  6. Bus via Madison

    1. Take the bus from Mall of America - IKEA - Bloomington to Madison, WI-Lake St.bus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Louisville, KYbus bus
    19h 51m
    $133–202

Minneapolis Airport (MSP) to Louisville by bus and foot

Calendar14Weekly Services
Duration17h 31mAverage Duration
Ticket$112Cheapest Price
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Questions & Answers

Map of how to get from Minneapolis Airport (MSP) to Louisville.ExpandLaunch map view
  • Distance: 608 mi
  • Duration: 3h 5m

What companies run services between Minneapolis Airport (MSP), USA and Louisville, KY, USA?

Delta, Southwest Airlines, and United Airlines fly from Minneapolis–Saint Paul International Airport (MSP) to Louisville International Airport (SDF) every 4 hours. Alternatively, you can take a bus from MSP Terminal 1 Transit Station to Louisville, KY via Union Depot Station & Terminal, Saint Paul Union Depot, Chicago Bus Station, and Chicago Union Station in around 17h 31m.

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